Literature DB >> 16769023

Prostaglandin F2alpha increases the sensitivity of the contractile proteins to Ca2+ in human myometrium.

Nicola A Woodcock1, Colin W Taylor, Steven Thornton.   

Abstract

It is not known whether agonists (other than oxytocin) increase the contractile protein sensitivity to intracellular calcium ([Ca2+]i) in human myometrium. We determined the calcium-tension relationship in the presence and absence of prostaglandin F2alpha (PGF2alpha). PGF2alpha increased the calcium sensitivity during both the contractile (rising) and relaxation (falling) phases of a contraction.

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Year:  2006        PMID： 16769023     DOI： 10.1016/j.ajog.2006.03.099

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN： 0002-9378            Impact factor:   8.661


  8 in total

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Authors:  Michael J Taggart; Kathleen G Morgan
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Review 2.  A close look at the contraction and relaxation of the myometrium; the role of calcium.

Authors:  Bilge Pehlivanoğlu; Sibel Bayrak; Murat Doğan
Journal:  J Turk Ger Gynecol Assoc       Date:  2013-12-01

3.  Umbilical cord prostaglandins in term and preterm parturition.

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Journal:  J Matern Fetal Neonatal Med       Date:  2015-03-23

4.  Hypoxia-induced force increase (HIFI) is a novel mechanism underlying the strengthening of labor contractions, produced by hypoxic stresses.

Authors:  Mohammed Alotaibi; Sarah Arrowsmith; Susan Wray
Journal:  Proc Natl Acad Sci U S A       Date:  2015-07-20       Impact factor: 11.205

5.  An elevated amniotic fluid prostaglandin F2α concentration is associated with intra-amniotic inflammation/infection, and clinical and histologic chorioamnionitis, as well as impending preterm delivery in patients with preterm labor and intact membranes.

Authors:  Jee Yoon Park; Roberto Romero; JoonHo Lee; Piya Chaemsaithong; Noppadol Chaiyasit; Bo Hyun Yoon
Journal:  J Matern Fetal Neonatal Med       Date:  2015-12-15

Review 6.  The uterine myocyte as a target for prevention of preterm birth.

Authors:  B F Mitchell; H N Aguilar; A Mosher; S Wood; D M Slater
Journal:  Facts Views Vis Obgyn       Date:  2013

7.  Characterization of the molecular and electrophysiological properties of the T-type calcium channel in human myometrium.

Authors:  Andrew M Blanks; Zheng-Hang Zhao; Anatoly Shmygol; Gilles Bru-Mercier; Shirley Astle; Steven Thornton
Journal:  J Physiol       Date:  2007-04-19       Impact factor: 5.182

8.  Rho-kinase mediates diphosphorylation of myosin regulatory light chain in cultured uterine, but not vascular smooth muscle cells.

Authors:  Hector N Aguilar; Curtis N Tracey; Barbara Zielnik; Bryan F Mitchell
Journal:  J Cell Mol Med       Date:  2012-12       Impact factor: 5.310
  8 in total

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