Literature DB >> 16767929

Functional results of a personal technique of reconstruction after pancreaticoduodenectomy.

R Caronna1, M Cardi, P Sammartino, S Mangioni, G Pittau, S Scozzafava, S Catinelli, P Chirletti, V Stipa.   

Abstract

The aim of the study is to propose a new technique of reconstruction after pancreaticoduodenectomy with more attention to the functional aspects. From 1995 and 2003, 25 patients underwent pancreaticoduodenectomy for pancreatic or periampullary cancer. The reconstruction was carried out by: end-to-end gastro-jejunal anastomosis (first jejunal loop); a Roux-en-Y T-T pancreatico-jejunal anastomosis leaving a silastic catheter in the Wirsung; hepatico-jejunostomy and jejuno-jejunostomy below the biliary anastomosis; superselective vagotomy. Mortality was 8%. Regarding the complications, we observed 3 biliary fistulas, mean duration 5 days, with spontaneous healing; 8 pleural effusions and 7 wound infections. Postoperative 3 months reevaluation showed weight gain in 14 patients with no other digestive symptoms (vomiting, fullness, dumping). With a scintigraphic meal we observed a good rythmic and regular gastric emptying. No jejunal peptic ulcers were noted in all patients after the gastric protonic pump inhibitors were discontinued. Fecal fats were evaluated in all cases for malabsorption 3 months after operation with low fat fecal levels. The preliminary results of our recent experience seem to be encouraging. This technique may have a useful application in the clinical setting as far as radicality and quality of life of the patients with pancreaticoduodenectomy.

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Mesh:

Year:  2003        PMID: 16767929

Source DB:  PubMed          Journal:  J Exp Clin Cancer Res        ISSN: 0392-9078


  7 in total

1.  Pancreaticojejunostomy with application of fibrinogen/thrombin-coated collagen patch (TachoSil) in Roux-en-Y reconstruction after pancreaticoduodenectomy.

Authors:  Piero Chirletti; Roberto Caronna; Gianfranco Fanello; Monica Schiratti; Franco Stagnitti; Nadia Peparini; Michele Benedetti; Gabriele Martino
Journal:  J Gastrointest Surg       Date:  2009-04-18       Impact factor: 3.452

2.  Does antecolic reconstruction decrease delayed gastric emptying after pancreatoduodenectomy?

Authors:  Nadia Peparini; Piero Chirletti
Journal:  World J Gastroenterol       Date:  2012-12-07       Impact factor: 5.742

Review 3.  Is antisecretory therapy after pancreatoduodenectomy necessary? Meta-analysis and contemporary practices of pancreatic surgeons.

Authors:  James R Butler; Tyrone Rogers; George Eckart; Gregory R Martens; Eugene P Ceppa; Michael G House; Attila Nakeeb; C Max Schmidt; Nicholas J Zyromski
Journal:  J Gastrointest Surg       Date:  2015-02-18       Impact factor: 3.452

Review 4.  Delayed Gastric Emptying and Gastric Remnant Function After Pancreaticoduodenectomy: A Systematic Review of Objective Assessment Modalities.

Authors:  Tim H-H Wang; Anthony Y Lin; Keno Mentor; Gregory O'Grady; Sanjay Pandanaboyana
Journal:  World J Surg       Date:  2022-10-23       Impact factor: 3.282

5.  Pancreaticojejuno anastomosis after pancreaticoduodenectomy: brief pathophysiological considerations for a rational surgical choice.

Authors:  Roberto Caronna; Nadia Peparini; Gabriele Cosimo Russillo; Adolfo Antonio Rogano; Giuseppe Dinatale; Piero Chirletti
Journal:  Int J Surg Oncol       Date:  2012-03-05

6.  Effect of surgery on pancreatic tumor-dependent lymphocyte asset: modulation of natural killer cell frequency and cytotoxic function.

Authors:  Francesco Iannone; Alessandra Porzia; Giovanna Peruzzi; Patrizia Birarelli; Bernardina Milana; Luca Sacco; Giuseppe Dinatale; Nadia Peparini; Giampaolo Prezioso; Simone Battella; Roberto Caronna; Stefania Morrone; Gabriella Palmieri; Fabrizio Mainiero; Piero Chirletti
Journal:  Pancreas       Date:  2015-04       Impact factor: 3.327

7.  Invaginated Pancreaticojejunostomy via the Space Behind the Root of Superior Mesenteric Vessels.

Authors:  Fu Tian Du; Wei Ding; Hong Feng Lin; Xiao Xia Gong; Sen Li; Qin Hua Song
Journal:  Gastroenterology Res       Date:  2011-03-20
  7 in total

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