Literature DB >> 16766757

Do ITPA and TPMT genotypes predict the development of side effects to AZA?

J A Duley, A M Marinaki, M Arenas, T H J Florin.   

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Year:  2006        PMID: 16766757      PMCID: PMC1856351     

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


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  8 in total

1.  Pitfalls in the determination of mutant alleles of the thiopurine methyltransferase gene.

Authors:  C Brouwer; A M Marinaki; L H Lambooy; J A Duley; M Shobowale-Bakre; R A De Abreu
Journal:  Leukemia       Date:  2001-11       Impact factor: 11.528

2.  ITPA genotyping test does not improve detection of Crohn's disease patients at risk of azathioprine/6-mercaptopurine induced myelosuppression.

Authors:  D Allorge; R Hamdan; F Broly; C Libersa; J-F Colombel
Journal:  Gut       Date:  2005-04       Impact factor: 23.059

3.  Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice.

Authors:  R B Gearry; M L Barclay; R L Roberts; J Harraway; M Zhang; L S Pike; P M George; C M Florkowski
Journal:  Intern Med J       Date:  2005-10       Impact factor: 2.048

4.  Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study.

Authors:  Nicolas von Ahsen; Victor W Armstrong; Christoph Behrens; Christian von Tirpitz; Andreas Stallmach; Hans Herfarth; Jürgen Stein; Peter Bias; Guido Adler; Maria Shipkova; Michael Oellerich; Wolfgang Kruis; Max Reinshagen; Ekkehard Schütz
Journal:  Clin Chem       Date:  2005-10-07       Impact factor: 8.327

5.  Liquid chromatography-tandem mass spectrometry analysis of erythrocyte thiopurine nucleotides and effect of thiopurine methyltransferase gene variants on these metabolites in patients receiving azathioprine/6-mercaptopurine therapy.

Authors:  Thierry Dervieux; Gary Meyer; Robert Barham; Mariko Matsutani; Mary Barry; Roselyne Boulieu; Bruce Neri; Ernest Seidman
Journal:  Clin Chem       Date:  2005-09-15       Impact factor: 8.327

Review 6.  Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy?

Authors:  Jeremy Sanderson; Azhar Ansari; Tony Marinaki; John Duley
Journal:  Ann Clin Biochem       Date:  2004-07       Impact factor: 2.057

7.  Erythrocyte thiopurine methyl transferase assessment prior to azathioprine use in the UK.

Authors:  S A Holme; J A Duley; J Sanderson; P A Routledge; A V Anstey
Journal:  QJM       Date:  2002-07

8.  Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).

Authors:  Anthony M Marinaki; Azhar Ansari; John A Duley; Monica Arenas; Satoshi Sumi; Cathryn M Lewis; El-Monsor Shobowale-Bakre; Emilia Escuredo; Lynette D Fairbanks; Jeremy D Sanderson
Journal:  Pharmacogenetics       Date:  2004-03
  8 in total
  3 in total

1.  Pretreatment determination of TPMT--state of the art in clinical practice.

Authors:  A Teml; E Schaeffeler; M Schwab
Journal:  Eur J Clin Pharmacol       Date:  2009-02-07       Impact factor: 2.953

2.  Functional study of the P32T ITPA variant associated with drug sensitivity in humans.

Authors:  Elena I Stepchenkova; Elena R Tarakhovskaya; Kathryn Spitler; Christin Frahm; Miriam R Menezes; Peter D Simone; Carol Kolar; Luis A Marky; Gloria E O Borgstahl; Youri I Pavlov
Journal:  J Mol Biol       Date:  2009-07-23       Impact factor: 5.469

3.  Elevated Levels of DNA Strand Breaks Induced by a Base Analog in the Human Cell Line with the P32T ITPA Variant.

Authors:  Irina S-R Waisertreiger; Miriam R Menezes; James Randazzo; Youri I Pavlov
Journal:  J Nucleic Acids       Date:  2010-09-26
  3 in total

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