Literature DB >> 16765595

Synthesis and antitumor activity of two natural N-acetylglucosamine-bearing triterpenoid saponins: lotoidoside D and E.

Mao-Cai Yan1, Yang Liu, Hong Chen, Ying Ke, Qing-Chun Xu, Mao-Sheng Cheng.   

Abstract

Two natural triterpenoid saponins bearing N-acetylglucosamine, lotoidoside D and lotoidoside E, which had been available only from Glinus lotoides growing in Egyptian desert, were facilely synthesized from readily available oleanolic acid. Preliminary pharmacological research showed their antitumor activity against HeLa cell.

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Year:  2006        PMID: 16765595     DOI: 10.1016/j.bmcl.2006.05.086

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  7 in total

1.  Abiotic elicitation of gymnemic acid in the suspension cultures of Gymnema sylvestre.

Authors:  Bhuvaneswari Ch; Kiranmayee Rao; Suryakala Gandi; Archana Giri
Journal:  World J Microbiol Biotechnol       Date:  2011-09-04       Impact factor: 3.312

Review 2.  Production of plant bioactive triterpenoid saponins: elicitation strategies and target genes to improve yields.

Authors:  Anna C A Yendo; Fernanda de Costa; Grace Gosmann; Arthur G Fett-Neto
Journal:  Mol Biotechnol       Date:  2010-09       Impact factor: 2.695

3.  Comparative transcriptomic analysis of genes in the triterpene saponin biosynthesis pathway in leaves and roots of Ardisia kteniophylla A. DC., a plant used in traditional Chinese medicine.

Authors:  Yuyang Lei; A J Harris; Aihua Wang; Liyun Zhao; Ming Luo; Ji Li; Hongfeng Chen
Journal:  Ecol Evol       Date:  2022-05-19       Impact factor: 3.167

4.  Synthesis and anti-cancer activity of a glycosyl library of N-acetylglucosamine-bearing oleanolic acid.

Authors:  Yi-Bing Zeng; Hsin-Min Hsiao; She-Hung Chan; Ying-Hsin Wang; You-Yu Lin; Yu-Hsuan Kuo; Jih-Hwa Guh; Pi-Hui Liang
Journal:  Mol Divers       Date:  2013-09-25       Impact factor: 2.943

5.  N-Alkyl derivatives of diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside; synthesis and antimicrobial activity.

Authors:  Agata Walczewska; Daria Grzywacz; Dorota Bednarczyk; Małgorzata Dawgul; Andrzej Nowacki; Wojciech Kamysz; Beata Liberek; Henryk Myszka
Journal:  Beilstein J Org Chem       Date:  2015-05-22       Impact factor: 2.883

Review 6.  Synthesis, Modification and Biological Activity of Diosgenyl β-d-Glycosaminosides: An Overview.

Authors:  Daria Grzywacz; Beata Liberek; Henryk Myszka
Journal:  Molecules       Date:  2020-11-20       Impact factor: 4.411

7.  Facile synthesis of oleanolic acid monoglycosides and diglycosides.

Authors:  Yu Sha; Mao-Cai Yan; Jiao Liu; Yang Liu; Mao-Sheng Cheng
Journal:  Molecules       Date:  2008-07-22       Impact factor: 4.411

  7 in total

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