Literature DB >> 16765444

Origin of Mexican Nahuas (Aztecs) according to HLA genes and their relationships with worldwide populations.

Gilberto Vargas-Alarcon1, Juan Moscoso, Jorge Martinez-Laso, Jose Manuel Rodriguez-Perez, Carmina Flores-Dominguez, Juan Ignacio Serrano-Vela, Almudena Moreno, Julio Granados, Antonio Arnaiz-Villena.   

Abstract

A Nahua Aztec isolated group from Morelos State (Mexico) was studied for their HLA profile. The relationship with other Amerindians and worldwide populations was studied by using 13,818 chromosomes and calculating Nei's chord genetic distances (DA), neighbor-joining dendrograms and correspondence multidimensional values. Three new HLA extended haplotypes were found in our group: A*30-B*49-DRB1*1001-DQB1*0501 (the most frequent one in this population), A*02-B*52-DRB1*1402-DQB1*0301 and A*68-B*61-DRB1*1602-DQB1*0303. Both genetic distances and correspondence analyses clearly show that our Nahua isolated group is genetically close to some of the most ancient groups living in Mexico (Mayans, Zapotecans, Mixtecans). This suggests that Nahua language (Nahuatl) may have been imposed to scattered groups throughout Mexico; otherwise Aztecs may have been living in Mexico long before their postulated immigration in the XII century AD.

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Year:  2006        PMID: 16765444     DOI: 10.1016/j.molimm.2006.04.014

Source DB:  PubMed          Journal:  Mol Immunol        ISSN: 0161-5890            Impact factor:   4.407


  13 in total

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3.  PPARG-LYPLAL1 Multi-Allelic Combination Associated with Obesity and Overweight in Mexican Adolescent Females.

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4.  The Origin of Amerindians and the Peopling of the Americas According to HLA Genes: Admixture with Asian and Pacific People.

Authors:  A Arnaiz-Villena; C Parga-Lozano; E Moreno; C Areces; D Rey; P Gomez-Prieto
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Journal:  PLoS One       Date:  2015-05-04       Impact factor: 3.240

8.  Y chromosome diversity in Aztlan descendants and its implications for the history of Central Mexico.

Authors:  Rocío Gómez; Miguel G Vilar; Marco Antonio Meraz-Ríos; David Véliz; Gerardo Zúñiga; Esther Alhelí Hernández-Tobías; Maria Del Pilar Figueroa-Corona; Amanda C Owings; Jill B Gaieski; Theodore G Schurr
Journal:  iScience       Date:  2021-04-30

9.  Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia.

Authors:  Gilberto Vargas-Alarcón; José-Manuel Fragoso; David Cruz-Robles; Angélica Vargas; Alfonso Vargas; José-Ignacio Lao-Villadóniga; Ferrán García-Fructuoso; Manuel Ramos-Kuri; Fernando Hernández; Rashidi Springall; Rafael Bojalil; Maite Vallejo; Manuel Martínez-Lavín
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10.  HLA Genes in Mayos Population from Northeast Mexico.

Authors:  A Arnaiz-Villena; J Moscoso; J Granados; J I Serrano-Vela; A de la Peña; R Reguera; A Ferri; E Seclen; R Izaguirre; N Perez-Hernandez; G Vargas-Alarcon
Journal:  Curr Genomics       Date:  2007-11       Impact factor: 2.236

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