Literature DB >> 16765435

Practical application of a chromogenic FXIIa assay.

Rui Zhuo1, Erwin A Vogler.   

Abstract

Autohydrolysis of blood factor XII (FXII+FXIIa-->2FXIIa) is found to be a facile reaction in neat-buffer buffer solutions of FXII but an insignificant reaction in the presence of plasma proteins. Autohydrolysis causes a chromogenic assay for FXIIa in buffer solution to strongly deviate from the traditional plasma-coagulation assay. Autohydrolysis can be accommodated by performing chromogenic detection of FXIIa as a rate assay in swamping concentrations of FXII. Rate-assay results performed in this way are shown to be in analytical agreement with the plasma-coagulation assay. Autohydrolysis can be used as a means of amplifying FXIIa produced by contacting neat-buffer solutions of FXII with biomaterials, suggesting a route to highly sensitive measurement of biomaterial hemocompatibility.

Mesh：

Substances：

Year:  2006        PMID： 16765435     DOI： 10.1016/j.biomaterials.2006.05.008

Source DB:  PubMed          Journal:  Biomaterials        ISSN： 0142-9612            Impact factor:   12.479


  9 in total

1.  Amidolytic, procoagulant, and activation-suppressing proteins produced by contact activation of blood factor XII in buffer solution.

Authors:  Avantika Golas; Chyi-Huey Joshua Yeh; Christopher A Siedlecki; Erwin A Vogler
Journal:  Biomaterials       Date:  2011-09-28       Impact factor: 12.479

2.  Competitive-protein adsorption in contact activation of blood factor XII.

Authors:  Rui Zhuo; Christopher A Siedlecki; Erwin A Vogler
Journal:  Biomaterials       Date:  2007-07-20       Impact factor: 12.479

3.  Contact activation of blood plasma and factor XII by ion-exchange resins.

Authors:  Chyi-Huey Josh Yeh; Ziad O Dimachkie; Avantika Golas; Alice Cheng; Purnendu Parhi; Erwin A Vogler
Journal:  Biomaterials       Date:  2011-10-06       Impact factor: 12.479

4.  Proteins, platelets, and blood coagulation at biomaterial interfaces.

Authors:  Li-Chong Xu; James W Bauer; Christopher A Siedlecki
Journal:  Colloids Surf B Biointerfaces       Date:  2014-09-28       Impact factor: 5.268

5.  Surface-energy dependent contact activation of blood factor XII.

Authors:  Avantika Golas; Purnendu Parhi; Ziad O Dimachkie; Christopher A Siedlecki; Erwin A Vogler
Journal:  Biomaterials       Date:  2009-11-04       Impact factor: 12.479

6.  Contributions of contact activation pathways of coagulation factor XII in plasma.

Authors:  Kaushik Chatterjee; Zhe Guo; Erwin A Vogler; Christopher A Siedlecki
Journal:  J Biomed Mater Res A       Date:  2009-07       Impact factor: 4.396

7.  A comparison of blood factor XII autoactivation in buffer, protein cocktail, serum, and plasma solutions.

Authors:  Avantika Golas; Chyi-Huey Josh Yeh; Harit Pitakjakpipop; Christopher A Siedlecki; Erwin A Vogler
Journal:  Biomaterials       Date:  2012-10-30       Impact factor: 12.479

Review 8.  Contact activation of blood-plasma coagulation.

Authors:  Erwin A Vogler; Christopher A Siedlecki
Journal:  Biomaterials       Date:  2009-01-24       Impact factor: 12.479

9.  Moderation of prekallkrein-factor XII interactions in surface activation of coagulation by protein-adsorption competition.

Authors:  Kaushik Chatterjee; Jennifer L Thornton; James W Bauer; Erwin A Vogler; Christopher A Siedlecki
Journal:  Biomaterials       Date:  2009-06-23       Impact factor: 12.479
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.