OBJECTIVE: To compare the efficacy of the medical treatment to surgical uterine evacuation and patient satisfaction in each group. DESIGN: A randomized, controlled study. SETTING:An outpatient clinic in the Department of Gynecology and Obstetrics in Oulu University Hospital, Oulu, Finland. PATIENT(S): Ninety-eight eligible women who had had miscarriages. INTERVENTION(S): Medical treatment of miscarriage (n = 49) with 200 mg of mifepristone and 0.8 mg of misoprostol 1-3 days after the event or surgical uterine evacuation (n = 49). Questionnaires to collect data of experienced pain and patient satisfaction. MAIN OUTCOME MEASURE(S): The complete abortion rate with the primary treatment (primary outcome) and the patient satisfaction (secondary outcome). RESULT(S): The success rate was equal (100% in surgical and 90% in medical group). More infections were diagnosed in the surgical group. Surgically treated patients were more satisfied with the treatment (100% vs. 88%). Medical treatment was considered more painful and fewer patients (70% vs. 91%) would choose the medical method in the future. CONCLUSION(S): Medical treatment is an effective alternative to surgical treatment and increases the choice available to women. Surgical treatment is associated with more infections. More medically treated patients experienced pain and dissatisfaction.
RCT Entities:
OBJECTIVE: To compare the efficacy of the medical treatment to surgical uterine evacuation and patient satisfaction in each group. DESIGN: A randomized, controlled study. SETTING: An outpatient clinic in the Department of Gynecology and Obstetrics in Oulu University Hospital, Oulu, Finland. PATIENT(S): Ninety-eight eligible women who had had miscarriages. INTERVENTION(S): Medical treatment of miscarriage (n = 49) with 200 mg of mifepristone and 0.8 mg of misoprostol 1-3 days after the event or surgical uterine evacuation (n = 49). Questionnaires to collect data of experienced pain and patient satisfaction. MAIN OUTCOME MEASURE(S): The complete abortion rate with the primary treatment (primary outcome) and the patient satisfaction (secondary outcome). RESULT(S): The success rate was equal (100% in surgical and 90% in medical group). More infections were diagnosed in the surgical group. Surgically treated patients were more satisfied with the treatment (100% vs. 88%). Medical treatment was considered more painful and fewer patients (70% vs. 91%) would choose the medical method in the future. CONCLUSION(S): Medical treatment is an effective alternative to surgical treatment and increases the choice available to women. Surgical treatment is associated with more infections. More medically treated patients experienced pain and dissatisfaction.
Authors: Vanessa K Dalton; Lisa H Harris; Jason D Bell; Jay Schulkin; Jodi Steinauer; Melissa Zochowski; A Mark Fendrick Journal: Am J Obstet Gynecol Date: 2011-03-17 Impact factor: 8.661
Authors: Vanessa K Dalton; Lisa H Harris; Katherine J Gold; Lisa Kane-Low; Jay Schulkin; Ken Guire; A Mark Fendrick Journal: Am J Obstet Gynecol Date: 2010-03-15 Impact factor: 8.661
Authors: Shagufta Parveen; Zaffar Abbas Khateeb; S M Mufti; M A Shah; Vishal R Tandon; S Hakak; Z Singh; Shagufta Yasmeen; Shakeel A Mir; Rehana Tabasum; Nasreen Jan Journal: Indian J Pharmacol Date: 2011-04 Impact factor: 1.200
Authors: Marike Lemmers; Marianne Ac Verschoor; Bobae Veronica Kim; Martha Hickey; Juan C Vazquez; Ben Willem J Mol; James P Neilson Journal: Cochrane Database Syst Rev Date: 2019-06-17
Authors: Charlotte C Hamel; Steffi van Wessel; Alasdair Carnegy; Sjors F P J Coppus; Marc P M L Snijders; Justin Clark; Mark H Emanuel Journal: Acta Obstet Gynecol Scand Date: 2021-08-12 Impact factor: 4.544
Authors: Joyce van den Berg; Charlotte C Hamel; Marcus P Snijders; Sjors F Coppus; Frank P Vandenbussche Journal: BMC Pregnancy Childbirth Date: 2019-11-27 Impact factor: 3.007
Authors: Jay Ghosh; Argyro Papadopoulou; Adam J Devall; Hannah C Jeffery; Leanne E Beeson; Vivian Do; Malcolm J Price; Aurelio Tobias; Özge Tunçalp; Antonella Lavelanet; Ahmet Metin Gülmezoglu; Arri Coomarasamy; Ioannis D Gallos Journal: Cochrane Database Syst Rev Date: 2021-06-01