Literature DB >> 1676433

In vitro microdialysis: a novel technique for stimulated neurotransmitter release measurements.

C W Bradberry1, J S Sprouse, P W Sheldon, G K Aghajanian, R H Roth.   

Abstract

A novel microdialysis technique suitable for parallel measurements of neurotransmitter release and single unit recordings from brain slices is presented. The effects of 3,4-methylenedioxymethamphetamine (MDMA) on slices of dorsal raphe nucleus and frontal cortex in a perfusion chamber for electrophysiological measures were studied. MDMA caused measurable release of serotonin which, in the case of the dorsal raphe, was of similar duration as the period of reduced cell firing induced by MDMA. Tryptophan potentiated the action of MDMA. Possible additional applications of this technique are discussed.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1676433     DOI： 10.1016/0165-0270(91)90141-l

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN： 0165-0270            Impact factor:   2.390


  6 in total

1.  Serotonergic neurotransmission in the ventral hippocampus is enhanced by corticosterone and altered by chronic amphetamine treatment.

Authors:  J L Barr; G L Forster
Journal:  Neuroscience       Date:  2011-03-21       Impact factor: 3.590

2.  Minimizing tissue damage in electroosmotic sampling.

Authors:  Amy E Hamsher; Hongjuan Xu; Yifat Guy; Mats Sandberg; Stephen G Weber
Journal:  Anal Chem       Date:  2010-08-01       Impact factor: 6.986

3.  Monoamine oxidase inhibitors increase preferentially extracellular 5-hydroxytryptamine in the midbrain raphe nuclei. A brain microdialysis study in the awake rat.

Authors:  P Celada; F Artigas
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1993-06       Impact factor: 3.000

4.  A metabolic biofuel cell: conversion of human leukocyte metabolic activity to electrical currents.

Authors:  Gusphyl A Justin; Yingze Zhang; X Tracy Cui; Charles W Bradberry; Mingui Sun; Robert J Sclabassi
Journal:  J Biol Eng       Date:  2011-05-10       Impact factor: 4.355

5.  LRRK2 affects vesicle trafficking, neurotransmitter extracellular level and membrane receptor localization.

Authors:  Rossana Migheli; Maria Grazia Del Giudice; Ylenia Spissu; Giovanna Sanna; Yulan Xiong; Ted M Dawson; Valina L Dawson; Manuela Galioto; Gaia Rocchitta; Alice Biosa; Pier Andrea Serra; Maria Teresa Carri; Claudia Crosio; Ciro Iaccarino
Journal:  PLoS One       Date:  2013-10-22       Impact factor: 3.240

6.  Treatment with Cyclic AMP Activators Reduces Glioblastoma Growth and Invasion as Assessed by Two-Photon Microscopy.

Authors:  Krista Minéia Wartchow; Benjamin Schmid; Philipp Tripal; Andreas Stadlbauer; Michael Buchfelder; Carlos-Alberto Gonçalves; Andrea Kleindienst
Journal:  Cells       Date:  2021-03-04       Impact factor: 6.600
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.