Literature DB >> 16764017

Requirements for effective IgE cross-linking on mast cells and basophils.

Edward F Knol1.   

Abstract

This article reviews the characteristics of high affinity IgE receptors (FcepsilonRI) and their role in the response to allergenic proteins. The requirements for successful cross-linking of FcepsilonRI on basophils and mast cells and subsequent degranulation by allergenic proteins will be explained in detail. Methods for in vitro analysis of allergen-induced mast cell and basophil degranulation will be described and issues/problems in applying these methods will be discussed. Finally, implications for manipulation of protein allergens will be discussed.

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Year:  2006        PMID： 16764017     DOI： 10.1002/mnfr.200500272

Source DB:  PubMed          Journal:  Mol Nutr Food Res        ISSN： 1613-4125            Impact factor:   5.914


  17 in total

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4.  Effector activity of peanut allergens: a critical role for Ara h 2, Ara h 6, and their variants.

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Review 8.  Physiological and Pathological Inflammation Induced by Antibodies and Pentraxins.

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