| Literature DB >> 16763897 |
F Djouadi1, F Aubey, D Schlemmer, S Gobin, P Laforet, R J A Wanders, A W Strauss, J P Bonnefont, J Bastin.
Abstract
Exposure to fibrates leads to normalization of fatty acid oxidation (FAO) in fibroblasts from patients with myopathic forms of CPT2 deficiency or VLCAD deficiency. Correction of FAO is related to a drug-induced increase of residual enzyme activity, and this could provide a new treatment strategy for these disorders.Entities:
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Year: 2006 PMID： 16763897 DOI： 10.1007/s10545-006-0266-3
Source DB: PubMed Journal: J Inherit Metab Dis ISSN： 0141-8955 Impact factor: 4.982