Literature DB >> 1676389

Cloning and characterisation of the Saccharomyces cerevisiae glycerol-3-phosphate dehydrogenase (GUT2) promoter.

D Sleep1, J E Ogden, N A Roberts, A R Goodey.   

Abstract

The Saccharomyces cerevisiae glycerol-3-phosphate dehydrogenase (GUT2) promoter and part of the protein-coding region have been isolated on a 6.3-kb genomic DNA fragment. Nucleotide sequence analysis shows that the promoter has many structural features in common with yeast glycolytic enzyme promoters. Chromosomal mapping indicates that this genomic fragment is located on chromosome XII. The GUT2 promoter has been used to construct a recombinant human albumin (reHA) secretion vector; yeast transformed with this vector secrete reHA into the culture supernatant.

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Year:  1991        PMID: 1676389     DOI: 10.1016/0378-1119(91)90228-4

Source DB:  PubMed          Journal:  Gene        ISSN: 0378-1119            Impact factor:   3.688


  7 in total

Review 1.  Pharmaceutical strategies utilizing recombinant human serum albumin.

Authors:  Victor Tuan Giam Chuang; Ulrich Kragh-Hansen; Masaki Otagiri
Journal:  Pharm Res       Date:  2002-05       Impact factor: 4.200

2.  Cloning, sequence, and disruption of the Saccharomyces diastaticus DAR1 gene encoding a glycerol-3-phosphate dehydrogenase.

Authors:  H T Wang; P Rahaim; P Robbins; R R Yocum
Journal:  J Bacteriol       Date:  1994-11       Impact factor: 3.490

3.  Identification of potential target genes for Adr1p through characterization of essential nucleotides in UAS1.

Authors:  C Cheng; N Kacherovsky; K M Dombek; S Camier; S K Thukral; E Rhim; E T Young
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272

4.  GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway.

Authors:  J Albertyn; S Hohmann; J M Thevelein; B A Prior
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272

5.  Cloning and characterization of seven cDNAs for hyperosmolarity-responsive (HOR) genes of Saccharomyces cerevisiae.

Authors:  T Hirayama; T Maeda; H Saito; K Shinozaki
Journal:  Mol Gen Genet       Date:  1995-11-15

6.  Modulation of chaperone gene expression in mutagenized Saccharomyces cerevisiae strains developed for recombinant human albumin production results in increased production of multiple heterologous proteins.

Authors:  T Payne; C Finnis; L R Evans; D J Mead; S V Avery; D B Archer; D Sleep
Journal:  Appl Environ Microbiol       Date:  2008-10-17       Impact factor: 4.792

7.  New nucleotide sequence data on the EMBL File Server.

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Journal:  Nucleic Acids Res       Date:  1991-11-11       Impact factor: 16.971

  7 in total

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