BACKGROUND: The relation between diabetes mellitus (DM) and mortality among patients with acute myocardial infarction is still controversial. We evaluated the influence of DM on the in-hospital mortality of acute myocardial infarction (AMI) patients using data from the Tokai Acute Myocardial Infarction Study-II, a multi-hospital prospective study performed in Japan. METHODS: All of the study subjects were patients hospitalized for newly diagnosed AMI at 1 of 13 acute care hospitals between January of 2001 and December of 2003. We abstracted the baseline and procedural characteristics from detailed chart reviews. Multivariate analysis was performed, controlling for the variables found to be significantly different between AMI patients with and without DM by chi-square test or unpaired t-test. We evaluated a total of 940 DM and 2284 non-DM patients. RESULTS: DM patients had roughly twice the in-hospital mortality rate of non-DM patients, with an unadjusted odds ratio of 1.77 (95% CI, 1.37-2.30). However, according to the multivariate analysis, DM was not identified as an independent predictor of in-hospital death, with an adjusted odds ratio of 5.73 (95% CI, 0.97-33.88). CONCLUSIONS: DM is not an independent predictor of in-hospital mortality, and that there is a need for additional studies to confirm our conclusion.
BACKGROUND: The relation between diabetes mellitus (DM) and mortality among patients with acute myocardial infarction is still controversial. We evaluated the influence of DM on the in-hospital mortality of acute myocardial infarction (AMI) patients using data from the Tokai Acute Myocardial Infarction Study-II, a multi-hospital prospective study performed in Japan. METHODS: All of the study subjects were patients hospitalized for newly diagnosed AMI at 1 of 13 acute care hospitals between January of 2001 and December of 2003. We abstracted the baseline and procedural characteristics from detailed chart reviews. Multivariate analysis was performed, controlling for the variables found to be significantly different between AMI patients with and without DM by chi-square test or unpaired t-test. We evaluated a total of 940 DM and 2284 non-DMpatients. RESULTS:DMpatients had roughly twice the in-hospital mortality rate of non-DMpatients, with an unadjusted odds ratio of 1.77 (95% CI, 1.37-2.30). However, according to the multivariate analysis, DM was not identified as an independent predictor of in-hospital death, with an adjusted odds ratio of 5.73 (95% CI, 0.97-33.88). CONCLUSIONS:DM is not an independent predictor of in-hospital mortality, and that there is a need for additional studies to confirm our conclusion.
Authors: Keun-Ho Park; Youngkeun Ahn; Myung Ho Jeong; Shung Chull Chae; Seung Ho Hur; Young Jo Kim; In Whan Seong; Jei Keon Chae; Taek Jong Hong; Myeong Chan Cho; Jang Ho Bae; Seung Woon Rha; Yang Soo Jang Journal: Korean J Intern Med Date: 2012-05-31 Impact factor: 2.884
Authors: Ana Lopez-de-Andres; Rodrigo Jimenez-Garcia; Valentin Hernandez-Barrera; Isabel Jimenez-Trujillo; Carmen Gallardo-Pino; Angel Gil de Miguel; Pilar Carrasco-Garrido Journal: PLoS One Date: 2014-01-15 Impact factor: 3.240