Literature DB >> 16761279

Multiple roles for emerin: implications for Emery-Dreifuss muscular dystrophy.

James M Holaska1, Katherine L Wilson.   

Abstract

X-linked Emery-Dreifuss muscular dystrophy (X-EDMD) is inherited through mutations in EMD, which encodes a nuclear membrane protein named emerin. Emerin is expressed in most cells, but EDMD strikes specific tissues. This review summarizes growing evidence that emerin has roles in both tissue-specific gene regulation and the mechanical integrity of the nucleus and discusses how these roles might impact EDMD.

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Year:  2006        PMID： 16761279      PMCID： PMC2559942          DOI： 10.1002/ar.a.20334

Source DB:  PubMed          Journal:  Anat Rec A Discov Mol Cell Evol Biol        ISSN： 1552-4884


  54 in total

1.  The interaction and colocalization of Sam68 with the splicing-associated factor YT521-B in nuclear dots is regulated by the Src family kinase p59(fyn).

Authors:  A M Hartmann; O Nayler; F W Schwaiger; A Obermeier; S Stamm
Journal:  Mol Biol Cell       Date:  1999-11       Impact factor: 4.138

Review 2.  Transcriptional repression, apoptosis, human disease and the functional evolution of the nuclear lamina.

Authors:  M Cohen; K K Lee; K L Wilson; Y Gruenbaum
Journal:  Trends Biochem Sci       Date:  2001-01       Impact factor: 13.807

Review 3.  Emery-Dreifuss muscular dystrophy - a 40 year retrospective.

Authors:  A E Emery
Journal:  Neuromuscul Disord       Date:  2000-06       Impact factor: 4.296

Review 4.  Review: lamina-associated polypeptide 2 isoforms and related proteins in cell cycle-dependent nuclear structure dynamics.

Authors:  T Dechat; S Vlcek; R Foisner
Journal:  J Struct Biol       Date:  2000-04       Impact factor: 2.867

5.  C. elegans nuclear envelope proteins emerin, MAN1, lamin, and nucleoporins reveal unique timing of nuclear envelope breakdown during mitosis.

Authors:  K K Lee; Y Gruenbaum; P Spann; J Liu; K L Wilson
Journal:  Mol Biol Cell       Date:  2000-09       Impact factor: 4.138

6.  MAN1, an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerin.

Authors:  F Lin; D L Blake; I Callebaut; I S Skerjanc; L Holmer; M W McBurney; M Paulin-Levasseur; H J Worman
Journal:  J Biol Chem       Date:  2000-02-18       Impact factor: 5.157

7.  Direct interaction between emerin and lamin A.

Authors:  L Clements; S Manilal; D R Love; G E Morris
Journal:  Biochem Biophys Res Commun       Date:  2000-01-27       Impact factor: 3.575

8.  Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy.

Authors:  Tokuko Haraguchi; James M Holaska; Miho Yamane; Takako Koujin; Noriyo Hashiguchi; Chie Mori; Katherine L Wilson; Yasushi Hiraoka
Journal:  Eur J Biochem       Date:  2004-03

9.  Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

Authors:  Q Zhang; J N Skepper; F Yang; J D Davies; L Hegyi; R G Roberts; P L Weissberg; J A Ellis; C M Shanahan
Journal:  J Cell Sci       Date:  2001-12       Impact factor: 5.285

10.  Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less).

Authors:  E Nili; G S Cojocaru; Y Kalma; D Ginsberg; N G Copeland; D J Gilbert; N A Jenkins; R Berger; S Shaklai; N Amariglio; F Brok-Simoni; A J Simon; G Rechavi
Journal:  J Cell Sci       Date:  2001-09       Impact factor: 5.285
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  27 in total

Review 1.  Lamin-binding Proteins.

Authors:  Katherine L Wilson; Roland Foisner
Journal:  Cold Spring Harb Perspect Biol       Date:  2010-02-17       Impact factor: 10.005

2.  The nuclear envelope at a glance.

Authors:  Katherine L Wilson; Jason M Berk
Journal:  J Cell Sci       Date:  2010-06-15       Impact factor: 5.285

3.  An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture.

Authors:  James M Holaska; Katherine L Wilson
Journal:  Biochemistry       Date:  2007-07-10       Impact factor: 3.162

Review 4.  Nuclear shape, mechanics, and mechanotransduction.

Authors:  Kris Noel Dahl; Alexandre J S Ribeiro; Jan Lammerding
Journal:  Circ Res       Date:  2008-06-06       Impact factor: 17.367

Review 5.  Diseases of the Nucleoskeleton.

Authors:  James M Holaska
Journal:  Compr Physiol       Date:  2016-09-15       Impact factor: 9.090

6.  Structural protein 4.1R is integrally involved in nuclear envelope protein localization, centrosome-nucleus association and transcriptional signaling.

Authors:  Adam J Meyer; Donna K Almendrala; Minjoung M Go; Sharon Wald Krauss
Journal:  J Cell Sci       Date:  2011-04-12       Impact factor: 5.285

7.  Inner/Outer nuclear membrane fusion in nuclear pore assembly: biochemical demonstration and molecular analysis.

Authors:  Boris Fichtman; Corinne Ramos; Beth Rasala; Amnon Harel; Douglass J Forbes
Journal:  Mol Biol Cell       Date:  2010-10-06       Impact factor: 4.138

Review 8.  Emerin in health and disease.

Authors:  Adam J Koch; James M Holaska
Journal:  Semin Cell Dev Biol       Date:  2013-12-21       Impact factor: 7.727

9.  A recurrent inversion on the eutherian X chromosome.

Authors:  Mario Cáceres; Robert T Sullivan; James W Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-14       Impact factor: 11.205

10.  Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts.

Authors:  Ishita S Mehta; Manelle Amira; Amanda J Harvey; Joanna M Bridger
Journal:  Genome Biol       Date:  2010-01-13       Impact factor: 13.583
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