Literature DB >> 16759747

CART in the enteric nervous system.

Eva Ekblad1.   

Abstract

The expression, distribution, origin, projections, chemical coding and functions of cocaine and amphetamine-regulated transcript (CART) in the gastro-intestinal tract are reviewed. CART is extensively expressed in the enteric nervous system. Except from being a possible modulator of NO induced intestinal relaxation CART does not seem to play any pivotal role in intestinal motility. Accumulating evidence suggest CART to be neuroprotective, involved in survival and maintenance of enteric neurons. CART expression increases in atrophic intestine thus suggesting a role of CART in intestinal adaptation. In rat antral mucosa CART is expressed in gastrin cells indicating a hormonal role of gastric CART.

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Year:  2006        PMID： 16759747     DOI： 10.1016/j.peptides.2005.12.015

Source DB:  PubMed          Journal:  Peptides        ISSN： 0196-9781            Impact factor:   3.750


  19 in total

Review 1.  CART peptides: regulators of body weight, reward and other functions.

Authors:  G Rogge; D Jones; G W Hubert; Y Lin; M J Kuhar
Journal:  Nat Rev Neurosci       Date:  2008-10       Impact factor: 34.870

2.  Methamphetamine-induced paralytic ileus.

Authors:  Terri L Carlson; Timothy P Plackett; Ronald A Gagliano; Richard R Smith
Journal:  Hawaii J Med Public Health       Date:  2012-02

3.  Obese carboxypeptidase E knockout mice exhibit multiple defects in peptide hormone processing contributing to low bone mineral density.

Authors:  Niamh X Cawley; Tulin Yanik; Alicja Woronowicz; Weizhong Chang; Joan C Marini; Y Peng Loh
Journal:  Am J Physiol Endocrinol Metab       Date:  2010-05-11       Impact factor: 4.310

4.  Dependence of serotonergic and other nonadrenergic enteric neurons on norepinephrine transporter expression.

Authors:  Zhishan Li; Marc G Caron; Randy D Blakely; Kara G Margolis; Michael D Gershon
Journal:  J Neurosci       Date:  2010-12-08       Impact factor: 6.167

5.  Expression of Cocaine and Amphetamine Regulated Transcript (CART) in the Porcine Intramural Neurons of Stomach in the Course of Experimentally Induced Diabetes Mellitus.

Authors:  Michał Bulc; Sławomir Gonkowski; Jarosław Całka
Journal:  J Mol Neurosci       Date:  2015-08-13       Impact factor: 3.444

6.  CART peptide is a potential endogenous antioxidant and preferentially localized in mitochondria.

Authors:  Peizhong Mao; Charles K Meshul; Philippe Thuillier; Natalie R S Goldberg; P Hemachandra Reddy
Journal:  PLoS One       Date:  2012-01-03       Impact factor: 3.240

7.  The Influence of Low Doses of Zearalenone on Distribution of Selected Active Substances in Nerve Fibers Within the Circular Muscle Layer of Porcine Ileum.

Authors:  Sławomir Gonkowski; Kazimierz Obremski; Jaroslaw Calka
Journal:  J Mol Neurosci       Date:  2015-03-15       Impact factor: 3.444

Review 8.  Developmental programming of hypothalamic neuronal circuits: impact on energy balance control.

Authors:  Thanuja Gali Ramamoorthy; Ghazala Begum; Erika Harno; Anne White
Journal:  Front Neurosci       Date:  2015-04-21       Impact factor: 4.677

Review 9.  CART in the regulation of appetite and energy homeostasis.

Authors:  Jackie Lau; Herbert Herzog
Journal:  Front Neurosci       Date:  2014-10-13       Impact factor: 4.677

10.  Characterisation of CART-containing neurons and cells in the porcine pancreas, gastro-intestinal tract, adrenal and thyroid glands.

Authors:  Nils Wierup; Anna Gunnarsdóttir; Eva Ekblad; Frank Sundler
Journal:  BMC Neurosci       Date:  2007-07-11       Impact factor: 3.288
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