Literature DB >> 16759178

Mitochondrial DNA portrait of Latvians: towards the understanding of the genetic structure of Baltic-speaking populations.

L Pliss1, K Tambets, E-L Loogväli, N Pronina, M Lazdins, A Krumina, V Baumanis, R Villems.   

Abstract

Mitochondrial DNA (mtDNA) variation was investigated in a sample of 299 Latvians, a Baltic-speaking population from Eastern Europe. Sequencing of the first hypervariable segment (HVS-I) in combination with analysis of informative coding region markers revealed that the vast majority of observed mtDNAs belong to haplogroups (hgs) common to most European populations. Analysis of the spatial distribution of mtDNA haplotypes found in Latvians, as well as in Baltic-speaking populations in general, revealed that they share haplotypes with all neighbouring populations irrespective of their linguistic affiliation. Hence, the results of our mtDNA analysis show that the previously described sharp difference between the Y-chromosomal hg N3 distribution in the paternally inherited gene pool of Baltic-speaking populations and of other European Indo-European speakers does not have a corresponding maternal counterpart.

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Substances:

Year:  2006        PMID: 16759178     DOI: 10.1111/j.1469-1809.2005.00238.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN: 0003-4800            Impact factor:   1.670


  12 in total

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Journal:  Am J Hum Genet       Date:  2007-02-06       Impact factor: 11.025

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4.  The Arrival of Siberian Ancestry Connecting the Eastern Baltic to Uralic Speakers further East.

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5.  Point mutations associated with Leber hereditary optic neuropathy in a Latvian population.

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7.  PSMA6 (rs2277460, rs1048990), PSMC6 (rs2295826, rs2295827) and PSMA3 (rs2348071) genetic diversity in Latvians, Lithuanians and Taiwanese.

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8.  Haplotype frequencies at the DRD2 locus in populations of the East European Plain.

Authors:  Olga V Flegontova; Andrey V Khrunin; Olga I Lylova; Larisa A Tarskaia; Victor A Spitsyn; Alexey I Mikulich; Svetlana A Limborska
Journal:  BMC Genet       Date:  2009-09-30       Impact factor: 2.797

9.  Uniparental genetic heritage of belarusians: encounter of rare middle eastern matrilineages with a central European mitochondrial DNA pool.

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Journal:  PLoS One       Date:  2013-06-13       Impact factor: 3.240

10.  Ancient DNA reveals prehistoric gene-flow from siberia in the complex human population history of North East Europe.

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Journal:  PLoS Genet       Date:  2013-02-14       Impact factor: 5.917

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