Literature DB >> 16758013

Reaction of arynes, N-heteroaromatics and nitriles.

Masilamani Jeganmohan1, Chien-Hong Cheng.   

Abstract

Various N-heteroaromatic compounds, including pyridines, quinolines and isoquinoline, react with arynes and nitrile-containing solvents to give N-arylated 1,2-dihydro-2-pyridinyl, -2-quinolinyl and -1-isoquinolinyl nitriles in excellent yields.

Year:  2006        PMID： 16758013     DOI： 10.1039/b602664h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Synthesis of pyrido[1,2-a]indole malonates and amines through aryne annulation.

Authors:  Donald C Rogness; Nataliya A Markina; Jesse P Waldo; Richard C Larock
Journal:  J Org Chem       Date:  2012-03-06       Impact factor: 4.354

2.  Intramolecular hydride transfer onto arynes: redox-neutral and transition metal-free C(sp3)-H functionalization of amines.

Authors:  Fahima I M Idiris; Cécile E Majesté; Gregory B Craven; Christopher R Jones
Journal:  Chem Sci       Date:  2018-02-08       Impact factor: 9.825

3.  Reactions of thermally generated benzynes with six-membered N-heteroaromatics: pathway and product diversity.

Authors:  Sahil Arora; Juntian Zhang; Vedamayee Pogula; Thomas R Hoye
Journal:  Chem Sci       Date:  2019-08-14       Impact factor: 9.825
  3 in total

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