Literature DB >> 16757632

Immune suppression as the etiology of failure to detect anti-HBc antibodies in patients with chronic hepatitis B virus infection.

V Avettand-Fenoel1, D Thabut, C Katlama, T Poynard, V Thibault.   

Abstract

A lack of anti-HBc antibodies during chronic hepatitis B virus infection is a serological pattern that is rarely observed. In our series of 39 patients with such a confirmed profile, mutations within the precore/core gene were rarely found and the lack of antibody detection was mostly explained by concurrent immunosuppression and the low sensitivities of the serological assays.

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Year:  2006        PMID： 16757632      PMCID： PMC1489430          DOI： 10.1128/JCM.00234-06

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  13 in total

1.  HBsAg carrier infants with serum anti-HBc negativity.

Authors:  S D Lee; K J Lo; Y T Tsai; J C Wu; T C Wu
Journal:  Hepatology       Date:  1989-01       Impact factor: 17.425

2.  Heterogeneity of hepatitis B virus (HBV) core gene in a patient with HBV-associated cirrhosis and serum negativity for anti-HBc.

Authors:  F Zoulim; X Zhang; C Pichoud; C Trepo
Journal:  J Hepatol       Date:  1996-02       Impact factor: 25.083

3.  A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness.

Authors:  L Stuyver; S De Gendt; C Van Geyt; F Zoulim; M Fried; R F Schinazi; R Rossau
Journal:  J Gen Virol       Date:  2000-01       Impact factor: 3.891

4.  Absence or delayed appearance of hepatitis B core antibody in chronic hepatitis B surface antigen carrier children.

Authors:  Y H Ni; H Y Hsu; M H Chang; D S Chen; C Y Lee
Journal:  J Hepatol       Date:  1993-02       Impact factor: 25.083

5.  Chronic hepatitis B virus infection in an anti-HBc-nonreactive blood donor: variant virus or defective immune response?

Authors:  J H Lee; T G Paglieroni; P V Holland; J B Zeldis
Journal:  Hepatology       Date:  1992-07       Impact factor: 17.425

6.  Hepatitis B surface antigen reactivity in man due to a new variant of hepatitis B virus.

Authors:  P Coursaget; B Yvonnet; C Bourdil; Y Buisson; J Chotard; R N'Doye; C Molinié; I Diop-Mar; J P Chiron
Journal:  Vaccine       Date:  1990-03       Impact factor: 3.641

7.  Molecular characterization of a new variant of hepatitis B virus in a persistently infected homosexual man.

Authors:  R A Bhat; P P Ulrich; G N Vyas
Journal:  Hepatology       Date:  1990-02       Impact factor: 17.425

8.  HBcAg expressed on the surface of circulating Dane particles in patients with hepatitis B virus infection without evidence of anti-HBc formation.

Authors:  B Möller; U Hopf; R Stemerowicz; G Henze; H Gelderblom
Journal:  Hepatology       Date:  1989-08       Impact factor: 17.425

9.  Conserved core protein sequences in hepatitis B virus infected patients without anti-HBc.

Authors:  M Melegari; M C Jung; R Schneider; T Santantonio; S Bagnulo; N Luchena; G Pastore; G Pape; P P Scaglioni; E Villa
Journal:  J Hepatol       Date:  1991-09       Impact factor: 25.083

10.  Nucleotide sequence of hepatitis B virus isolated from subjects without serum anti-hepatitis B core antibody.

Authors:  K Gotoh; S Mima; T Uchida; T Shikata; K Yoshizawa; M Irie; M Mizui
Journal:  J Med Virol       Date:  1995-07       Impact factor: 2.327
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  12 in total

Review 1.  The underlying mechanisms for the "isolated positivity for the hepatitis B surface antigen (HBsAg)" serological profile.

Authors:  Robério Amorim de Almeida Pondé
Journal:  Med Microbiol Immunol       Date:  2010-05-11       Impact factor: 3.402

Review 2.  Dynamic profile of the HBeAg-anti-HBe system in acute and chronic hepatitis B virus infection: A clinical-laboratory approach.

Authors:  Robério Amorim de Almeida Pondé
Journal:  Mol Biol Rep       Date:  2020-12-09       Impact factor: 2.316

3.  Hepatitis B Core Antibody Negativity in a Chronic Hepatitis B Infected Patient: Report of an Unusual Serological Pattern.

Authors:  Vijeta Bajpai; Ekta Gupta; Naveen Kundu; Shvetank Sharma; S M Shashtry
Journal:  J Clin Diagn Res       Date:  2017-08-01

4.  Reactivation of hepatitis B virus with mutated hepatitis B surface antigen in a liver transplant recipient receiving a graft from an antibody to hepatitis B surface antigen- and antibody to hepatitis B core antigen-positive donor.

Authors:  Annette Blaich; Michael Manz; Alexis Dumoulin; Christian G Schüttler; Hans H Hirsch; Wolfram H Gerlich; Reno Frei
Journal:  Transfusion       Date:  2012-02-08       Impact factor: 3.157

5.  Hepatitis B infection among HIV infected individuals in Gabon: Occult hepatitis B enhances HBV DNA prevalence.

Authors:  Berthold Bivigou-Mboumba; Marie Amougou-Atsama; Samira Zoa-Assoumou; Hervé M'boyis Kamdem; Guy Francis Nzengui-Nzengui; Angélique Ndojyi-Mbiguino; Richard Njouom; Sandrine François-Souquière
Journal:  PLoS One       Date:  2018-01-09       Impact factor: 3.240

6.  Hepatitis B serological markers and plasma DNA concentrations.

Authors:  Huw Price; David Dunn; Tamale Zachary; Tobias Vudriko; Michael Chirara; Cissy Kityo; Paula Munderi; Moira Spyer; James Hakim; Charles Gilks; Pontiano Kaleebu; Deenan Pillay; Richard Gilson
Journal:  AIDS       Date:  2017-05-15       Impact factor: 4.177

7.  Acute hepatitis B virus infection with delayed appearance of hepatitis B core antibody in an immunocompromised patient: a case report.

Authors:  Nicholas Brousseau; Donald G Murphy; Vladimir Gilca; Jacynthe Larouche; Sema Mandal; Richard S Tedder
Journal:  J Med Case Rep       Date:  2017-04-17

8.  Hepatitis B virus infection in human immunodeficiency virus infected southern African adults: occult or overt--that is the question.

Authors:  Trevor G Bell; Euphodia Makondo; Neil A Martinson; Anna Kramvis
Journal:  PLoS One       Date:  2012-10-01       Impact factor: 3.240

9.  Chronic hepatitis B and C co-infection increased all-cause mortality in HAART-naive HIV patients in Northern Thailand.

Authors:  N Tsuchiya; P Pathipvanich; A Rojanawiwat; N Wichukchinda; I Koga; M Koga; W Auwanit; P E Kilgore; K Ariyoshi; P Sawanpanyalert
Journal:  Epidemiol Infect       Date:  2012-11-01       Impact factor: 2.451

10.  Hepatitis B Virus (HBV) Infection and Re-activation During Nucleos(t)ide Reverse Transcriptase Inhibitor-Sparing Antiretroviral Therapy in a High-HBV Endemicity Setting.

Authors:  Adam Abdullahi; Olga Mafotsing Fopoussi; Judith Torimiro; Mark Atkins; Charles Kouanfack; Anna Maria Geretti
Journal:  Open Forum Infect Dis       Date:  2018-10-05       Impact factor: 3.835
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