Literature DB >> 16757627

Value of the chlorhexidine decontamination method for recovery of nontuberculous mycobacteria from sputum samples of patients with cystic fibrosis.

Agnès Ferroni1, Hoang Vu-Thien, Philippe Lanotte, Muriel Le Bourgeois, Isabelle Sermet-Gaudelus, Brigitte Fauroux, Sophie Marchand, Françoise Varaigne, Patrick Berche, Jean-Louis Gaillard, Catherine Offredo.   

Abstract

The chlorhexidine method was compared to the N-acetyl-l-cysteine-NaOH-oxalic acid decontamination method currently recommended for the recovery of nontuberculous mycobacteria (NTM) from patients with cystic fibrosis. Sputum samples (n = 827) treated with chlorhexidine yielded twice as many NTM-positive cultures as those treated by the reference method (54 [6.50%] versus 27 [3.25%]; P < 0.0001) despite a higher contamination rate (20% versus 14.2%; P = 0.0017).

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Year:  2006        PMID： 16757627      PMCID： PMC1489418          DOI： 10.1128/JCM.00285-06

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  17 in total

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