Literature DB >> 16757419

Life-threatening motor neurotoxicity in association with bortezomib.

Sunil Gupta, Antonio Pagliuca, Steve Devereux, Ghulam J Mufti, Steve Schey.   

Abstract

Bortezomib has been licensed to be used in relapsed and refractory multiple myeloma. It is a promising agent for this incurable condition but our effort is to caution hematologists about the life-threatening neurotoxicity (grade 4) which was seen in two of six patients treated with this agent although the complication cannot definitely be attributed to bortezomib.

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Year:  2006        PMID: 16757419

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


  2 in total

1.  Somatic and autonomic small fiber neuropathy induced by bortezomib therapy: an immunofluorescence study.

Authors:  Maria Pia Giannoccaro; Vincenzo Donadio; Carolina Gomis Pèrez; Walter Borsini; Vitantonio Di Stasi; Rocco Liguori
Journal:  Neurol Sci       Date:  2011-02-03       Impact factor: 3.307

Review 2.  Peripheral neuropathy and new treatments for multiple myeloma: background and practical recommendations.

Authors:  Bilal Mohty; Jean El-Cheikh; Ibrahim Yakoub-Agha; Philippe Moreau; Jean-Luc Harousseau; Mohamad Mohty
Journal:  Haematologica       Date:  2010-02       Impact factor: 9.941

  2 in total

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