Literature DB >> 16757408

Correspondence: Dimethylamine Borane Neurotoxicity and Authors' Response.

Chin-Chang Huang1, Hung-Chou Kuo, Yu-Tse Tsan, Dong-Zong Hung.   

Abstract

Correspondence on Dimethylamine Borane Neurotoxicity and authors' response.

Entities:  

Year:  2006        PMID: 16757408      PMCID: PMC1459955          DOI: 10.1289/ehp.114-a274b

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


The magnetic resonance imaging (MRI) studies of our patient (Tsan et al. 2005) were performed on the 8th and 37th days after DMAB poisoning and show marked differences. The lesions of the bilateral cerebellar periventricular area were revealed in every mode of images (fluid-attenuated inversion recovery, T2-weighted intensity, diffusion-weighted images, and T1WI) and were comparable with the patient’s symptoms and signs. The possibility of artifact is small. The changes in the serial MRI suggest a transient brain lesion, which may be due to transient demyelination, neuronal damage, or edema. We appreciate that Kuo et al. (in press) performed the nerve biopsy to prove the axonal polyneuropathy. Their result was comparable with those of our study: DMAB intoxication can lead to acute cortical, cerebellar lesions and polyneuropathy.
  2 in total

1.  Axonal polyneuropathy after acute dimethylamine borane intoxication.

Authors:  Hung-Chou Kuo; Chin-Chang Huang; Chun-Che Chu; Nai-Shin Chu
Journal:  Arch Neurol       Date:  2006-07

2.  Case report: the clinical toxicity of dimethylamine borane.

Authors:  Yu-Tse Tsan; Kai-Yu Peng; Dong-Zong Hung; Wei-Hsiung Hu; Dar-Yu Yang
Journal:  Environ Health Perspect       Date:  2005-12       Impact factor: 9.031

  2 in total

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