BACKGROUND: This randomized prospective study with blinded postanesthesia care unit (PACU) observers compared the recovery profiles in morbidly obese patients who receivedsevoflurane or desfluranefor maintenance of anesthesia in combination with a remifentanil target controlled infusion (TCI). METHODS:50 morbidly obese patients scheduled for laparoscopic gastric banding were included to receive BIS-guided sevoflurane or desflurane anesthesia with BIS-triggered inhalation boli in combination with remifentanil TCI. In the PACU, the following recovery scores were investigated: Modified Aldrete score, a modified Observers' Assessment of Alertness/Sedation Scale (OAA/S), pain numerical rating scale (NRS), oxygen saturation (SpO(2)) and postoperative nausea and vomiting (PONV). RESULTS:OAA/S and NRS pain scores showed a similar evolution in both groups from the moment of PACU admission up to 120 minutes after admission. In both groups, patients showed no serious hypoxemia during PACU stay. Incidence of PONV was shorter lasting in the sevoflurane group compared to the desflurane group. CONCLUSIONS: No clinically relevant difference was found in recovery in the PACU between morbidly obese patients anesthetized withdesflurane or sevoflurane. Both agents resulted in satisfactory recovery in morbidly obese patients.
RCT Entities:
BACKGROUND: This randomized prospective study with blinded postanesthesia care unit (PACU) observers compared the recovery profiles in morbidly obesepatients who received sevoflurane or desflurane for maintenance of anesthesia in combination with a remifentanil target controlled infusion (TCI). METHODS: 50 morbidly obesepatients scheduled for laparoscopic gastric banding were included to receive BIS-guided sevoflurane or desflurane anesthesia with BIS-triggered inhalation boli in combination with remifentanil TCI. In the PACU, the following recovery scores were investigated: Modified Aldrete score, a modified Observers' Assessment of Alertness/Sedation Scale (OAA/S), pain numerical rating scale (NRS), oxygen saturation (SpO(2)) and postoperative nausea and vomiting (PONV). RESULTS: OAA/S and NRS pain scores showed a similar evolution in both groups from the moment of PACU admission up to 120 minutes after admission. In both groups, patients showed no serious hypoxemia during PACU stay. Incidence of PONV was shorter lasting in the sevoflurane group compared to the desflurane group. CONCLUSIONS: No clinically relevant difference was found in recovery in the PACU between morbidly obesepatients anesthetized with desflurane or sevoflurane. Both agents resulted in satisfactory recovery in morbidly obesepatients.
Authors: Jonas Weber; Johannes Schmidt; Steffen Wirth; Stefan Schumann; James H Philip; Leopold H J Eberhart Journal: J Clin Monit Comput Date: 2020-02-17 Impact factor: 2.502
Authors: Stavros G Memtsoudis; Crispiana Cozowicz; Mahesh Nagappa; Jean Wong; Girish P Joshi; David T Wong; Anthony G Doufas; Meltem Yilmaz; Mark H Stein; Megan L Krajewski; Mandeep Singh; Lukas Pichler; Satya Krishna Ramachandran; Frances Chung Journal: Anesth Analg Date: 2018-10 Impact factor: 5.108