Literature DB >> 16755571

Cidofovir bladder instillation for the treatment of BK hemorrhagic cystitis after allogeneic stem cell transplantation.

Benjamin Bridges1, Sarah Donegan, Ashraf Badros.   

Abstract

We report a case of severe hemorrhagic cystitis after allogeneic transplantation in association with high BK viral load. After failure of aggressive hydration, platelet and blood transfusions, continuous bladder irrigation, and tapering of the immune suppression, we instilled cidofovir into the bladder, which resulted in decreased BK viral load and significant clinical improvement. Our case suggests that local cidofovir therapy for viral hemorrhagic cystitis is effective and well tolerated with no observed side effects.

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Year:  2006        PMID： 16755571     DOI： 10.1002/ajh.20567

Source DB:  PubMed          Journal:  Am J Hematol        ISSN： 0361-8609            Impact factor:   10.047


  11 in total

Review 1.  Polyomavirus BK infection in blood and marrow transplant recipients.

Authors:  L K Dropulic; R J Jones
Journal:  Bone Marrow Transplant       Date:  2007-10-22       Impact factor: 5.483

2.  Alkoxylalkyl Esters of Nucleotide Analogs Inhibit Polyomavirus DNA Replication and Large T Antigen Activities.

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Journal:  Antimicrob Agents Chemother       Date:  2021-02-17       Impact factor: 5.191

3.  Hemorrhagic cystitis: A challenge to the urologist.

Authors:  R Manikandan; Santosh Kumar; Lalgudi N Dorairajan
Journal:  Indian J Urol       Date:  2010-04

Review 4.  Viral lower urinary tract infections.

Authors:  Darius A Paduch
Journal:  Curr Urol Rep       Date:  2007-07       Impact factor: 3.092

Review 5.  The polyomavirus puzzle: is host immune response beneficial in controlling BK virus after adult hematopoietic cell transplantion?

Authors:  G Satyanarayana; F M Marty; C S Tan
Journal:  Transpl Infect Dis       Date:  2014-05-19       Impact factor: 2.228

Review 6.  The next ten stories on antiviral drug discovery (part E): advents, advances, and adventures.

Authors:  Erik De Clercq
Journal:  Med Res Rev       Date:  2011-01       Impact factor: 12.944

7.  Successful Treatment with Intravenous and Intravascular Cidofovir for BK Virus-Associated Hemorrhagic Cystitis after Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report.

Authors:  Azim Mehrvar; Ali Naderi; Narjes Mehrvar; Mahyar Nourian
Journal:  Case Rep Oncol       Date:  2021-06-17

Review 8.  Diagnosis and treatment of viral diseases in recipients of allogeneic hematopoietic stem cell transplantation.

Authors:  Ren Lin; Qifa Liu
Journal:  J Hematol Oncol       Date:  2013-12-17       Impact factor: 17.388

9.  A Novel Case of Symptomatic BK Viraemia in a Patient Undergoing Treatment for Hodgkin Lymphoma.

Authors:  Jacinta Perram; Jane Estell
Journal:  Case Rep Infect Dis       Date:  2014-06-24

10.  Nursing Management of Haemorrhagic Cystitis in Patients Undergoing Haematopoietic Stem Cell Transplantation: a Multicentre Italian Survey.

Authors:  Chiara Visintini; Margherita Venturini; Stefano Botti; Gianpaolo Gargiulo; Alvisa Palese
Journal:  Mediterr J Hematol Infect Dis       Date:  2019-09-01       Impact factor: 2.576
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