Literature DB >> 16755472

Outbreak of pertussis among healthcare workers in a hospital surgical unit.

F Brian Pascual1, Candace L McCall, Aaron McMurtray, Tony Payton, Forrest Smith, Kristine M Bisgard.   

Abstract

BACKGROUND: In September 1999, a pertussis outbreak was detected among surgical staff of a 138-bed community hospital. Patients were exposed to Bordetella pertussis during the 3-month outbreak period.
OBJECTIVE: To describe the outbreak among surgical staff, to evaluate implemented control measures, and to determine whether nosocomial transmission occurred.
METHODS: Clinical pertussis was defined as acute cough illness with a duration of 14 days or more without another apparent cause; persons with positive culture, PCR, or serologic test results were defined as having laboratory-confirmed pertussis. Surgical healthcare workers (HCWs) were interviewed regarding pertussis symptoms, and specimens were obtained for laboratory analysis. Patients exposed to B. pertussis during an ill staff member's 3-week infectious period were interviewed by phone to determine the extent of nosocomial spread. PARTICIPANTS: A total of 53 HCWs assigned to the surgical unit and 146 exposed patients. HCWs with pertussis were defined as case subjects; HCWs without pertussis were defined as non-case subjects.
RESULTS: Twelve (23%) of 53 HCWs had clinical pertussis; 6 cases were laboratory confirmed. The median cough duration in the 12 case subjects was 27 days (range, 20-120 days); 10 (83%) had paroxysms. Eleven (92%) of 12 case subjects and 28 (86%) of 41 non-case subjects received antibiotic treatment or prophylaxis. Seven case subjects (58%) reported they always wore a mask when near patients. Of 146 patients potentially exposed to pertussis from the 12 case subjects, 120 (82%) were interviewed; none reported a pertussis-like illness.
CONCLUSIONS: Surgical staff transmitted B. pertussis among themselves; self-reported data suggests that these HCWs did not transmit B. pertussis to their patients, likely because of mask use, cough etiquette, and limited face-to-face contact. Control measures might have helped limit the outbreak once pertussis was recognized.

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Year:  2006        PMID: 16755472     DOI: 10.1086/506232

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  7 in total

1.  Outbreak of pertussis among healthcare workers in a hospital maternity unit.

Authors:  Christina Petridou; Hazel Gray; Michael Heard; Lorna Sugden; Karen Davis-Blues; Nick Cortes; Mary Edwards; Kordo Saeed
Journal:  J Infect Prev       Date:  2017-02-01

2.  Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP).

Authors:  Jennifer L Liang; Tejpratap Tiwari; Pedro Moro; Nancy E Messonnier; Arthur Reingold; Mark Sawyer; Thomas A Clark
Journal:  MMWR Recomm Rep       Date:  2018-04-27

3.  Tdap Vaccination Among Healthcare Personnel, Internet Panel Survey, 2012-2014.

Authors:  Anup Srivastav; Carla L Black; Peng-Jun Lu; Jun Zhang; Jennifer L Liang; Stacie M Greby
Journal:  Am J Prev Med       Date:  2017-05-23       Impact factor: 5.043

4.  Tetanus, diphtheria and acellular pertussis (Tdap) vaccination among healthcare personnel-United States, 2011.

Authors:  Peng-jun Lu; Samuel B Graitcer; Alissa O'Halloran; Jennifer L Liang
Journal:  Vaccine       Date:  2013-12-03       Impact factor: 3.641

5.  Risk factors for pertussis in adults and teenagers in England.

Authors:  A Wensley; G J Hughes; H Campbell; G Amirthalingam; N Andrews; N Young; L Coole
Journal:  Epidemiol Infect       Date:  2017-01-09       Impact factor: 4.434

6.  Seroprevalence of Pertussis in Healthcare Workers without Adult Pertussis Vaccine Use at a University Hospital in Korea.

Authors:  Won Suk Choi; Su Hyun Kim; Dae Won Park
Journal:  J Korean Med Sci       Date:  2018-11-19       Impact factor: 2.153

7.  Efficacy of face masks and respirators in preventing upper respiratory tract bacterial colonization and co-infection in hospital healthcare workers.

Authors:  C Raina MacIntyre; Quanyi Wang; Bayzidur Rahman; Holly Seale; Iman Ridda; Zhanhai Gao; Peng Yang; Weixian Shi; Xinghuo Pang; Yi Zhang; Aye Moa; Dominic E Dwyer
Journal:  Prev Med       Date:  2014-01-25       Impact factor: 4.018

  7 in total

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