OBJECTIVES: The purpose of this article is to discuss the natural history, treatment, and outcomes for patients with aneurysmal bone cysts (ABC). METHODS: Review of the pertinent literature. RESULTS: ABCs account for 1% to 2% of all primary bone tumors, usually present in the first 2 decades of life, and exhibit a slight female preponderance. The majority of patients are treated with curettage with local control rates ranging from approximately 70% to 90%. Almost all patients with recurrences are salvaged by one or more additional operations. A small subset of patients is treated with marginal or wide excision and almost all are locally controlled. A few patients with incompletely resectable, aggressive, and/or recurrent ABCs are treated with low-dose (26-30 Gy) radiotherapy (RT) and are locally controlled in approximately 90% of cases. CONCLUSIONS: The mainstay of treatment is surgery and most patients are cured with one or more operations. A small subset of patients with incompletely resectable, aggressive, and/or recurrent ABCs may be cured with low-dose RT.
OBJECTIVES: The purpose of this article is to discuss the natural history, treatment, and outcomes for patients with aneurysmal bone cysts (ABC). METHODS: Review of the pertinent literature. RESULTS: ABCs account for 1% to 2% of all primary bone tumors, usually present in the first 2 decades of life, and exhibit a slight female preponderance. The majority of patients are treated with curettage with local control rates ranging from approximately 70% to 90%. Almost all patients with recurrences are salvaged by one or more additional operations. A small subset of patients is treated with marginal or wide excision and almost all are locally controlled. A few patients with incompletely resectable, aggressive, and/or recurrent ABCs are treated with low-dose (26-30 Gy) radiotherapy (RT) and are locally controlled in approximately 90% of cases. CONCLUSIONS: The mainstay of treatment is surgery and most patients are cured with one or more operations. A small subset of patients with incompletely resectable, aggressive, and/or recurrent ABCs may be cured with low-dose RT.
Authors: Khaled Elsayad; Jan Kriz; Heinrich Seegenschmiedt; Detlef Imhoff; Reinhard Heyd; Hans Theodor Eich; Oliver Micke Journal: Strahlenther Onkol Date: 2016-12-12 Impact factor: 3.621
Authors: Christian Breuer; Hanna Paul; André Zimmermann; Stefan Braunstein; Jörg Schaper; Ertan Mayatepek; Jun Oh Journal: Eur J Pediatr Date: 2010-01-27 Impact factor: 3.183
Authors: Juliane Richter; Sven K Tschöke; Jens Gulow; Uwe Eichfeld; Magdalena Wojan; Georg von Salis-Soglio; Christoph E Heyde Journal: Patient Saf Surg Date: 2011-08-26
Authors: Addy C M van de Luijtgaarden; Rene P H Veth; Piet J Slootweg; Pauline M Wijers-Koster; Leo J Schultze Kool; Judith V M G Bovee; Winette T A van der Graaf Journal: Virchows Arch Date: 2009-10-17 Impact factor: 4.064