Literature DB >> 1675489

Facilitation of the induction of long-term potentiation by GABAB receptors.

D D Mott1, D V Lewis.   

Abstract

Long-term potentiation (LTP), an in vitro model of learning, was induced in hippocampal slices by 5-hertz stimulation. During induction, gamma-aminobutyric acid A (GABAA) inhibition decreased, causing the N-methyl-D-aspartate receptor-mediated excitation to increase. 2-OH Saclofen, a GABAB receptor antagonist, prevented the reduction of inhibition, the increase of excitation, and the induction of LTP. Therefore, disinhibition caused by GABAB receptors is required for induction of LTP by 5-hertz stimulation. GABAB receptor modulation of synaptic plasticity occurs at frequencies in the range of the endogenous hippocampal theta rhythm, which has been shown to modulate LTP in vivo.

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Year:  1991        PMID： 1675489     DOI： 10.1126/science.1675489

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  59 in total

Review 1.  Synaptic plasticity in the hippocampus during afferent activation reproducing the pattern of the theta rhythm (theta plasticity).

Authors:  A M Kleshchevnikov
Journal:  Neurosci Behav Physiol       Date:  1999 Mar-Apr

Review 2.  Neurochemical and molecular pharmacological aspects of the GABA(B) receptor.

Authors:  K Kuriyama; M Hirouchi; H Kimura
Journal:  Neurochem Res       Date:  2000-10       Impact factor: 3.996

3.  Random response fluctuations lead to spurious paired-pulse facilitation.

Authors:  J Kim; B E Alger
Journal:  J Neurosci       Date:  2001-12-15       Impact factor: 6.167

4.  GABAB receptor antagonism: facilitatory effects on memory parallel those on LTP induced by TBS but not HFS.

Authors:  U Stäubli; J Scafidi; D Chun
Journal:  J Neurosci       Date:  1999-06-01       Impact factor: 6.167

5.  Calcium-dependent activator protein for secretion 2 (CAPS2) promotes BDNF secretion and is critical for the development of GABAergic interneuron network.

Authors:  Yo Shinoda; Tetsushi Sadakata; Kazuhito Nakao; Ritsuko Katoh-Semba; Emi Kinameri; Asako Furuya; Yuchio Yanagawa; Hajime Hirase; Teiichi Furuichi
Journal:  Proc Natl Acad Sci U S A       Date:  2010-12-20       Impact factor: 11.205

6.  Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction.

Authors:  Claudia A Grillo; Gerardo G Piroli; Ashlie N Evans; Victoria A Macht; Steven P Wilson; Karen A Scott; Randall R Sakai; David D Mott; Lawrence P Reagan
Journal:  Physiol Behav       Date:  2010-10-29

7.  Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice.

Authors:  P A Slesinger; M Stoffel; Y N Jan; L Y Jan
Journal:  Proc Natl Acad Sci U S A       Date:  1997-10-28       Impact factor: 11.205

8.  Simultaneous NMDA-dependent long-term potentiation of EPSCs and long-term depression of IPSCs in cultured rat hippocampal neurons.

Authors:  Miriam Ivenshitz; Menahem Segal
Journal:  J Neurosci       Date:  2006-01-25       Impact factor: 6.167

9.  GABAB receptors, monoamine receptors, and postsynaptic inositol trisphosphate-induced Ca2+ release are involved in the induction of long-term potentiation at visual cortical inhibitory synapses.

Authors:  Y Komatsu
Journal:  J Neurosci       Date:  1996-10-15       Impact factor: 6.167

10.  cAMP response element-binding protein, activating transcription factor-4, and upstream stimulatory factor differentially control hippocampal GABABR1a and GABABR1b subunit gene expression through alternative promoters.

Authors:  Janine L Steiger; Sabita Bandyopadhyay; David H Farb; Shelley J Russek
Journal:  J Neurosci       Date:  2004-07-07       Impact factor: 6.167
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