Literature DB >> 1675432

Genetic analysis of autoimmune type 1 diabetes mellitus in mice.

J A Todd1, T J Aitman, R J Cornall, S Ghosh, J R Hall, C M Hearne, A M Knight, J M Love, M A McAleer, J B Prins.   

Abstract

Two genes, Idd-3 and Idd-4, that influence the onset of autoimmune type 1 diabetes in the nonobese diabetic mouse have been located on chromosomes 3 and 11, outside the chromosome 17 major histocompatibility complex. A genetic map of the mouse genome, analysed using the polymerase chain reaction, has been assembled specifically for the study. On the basis of comparative maps of the mouse and human genomes, the homologue of Idd-3 may reside on human chromosomes 1 or 4 and Idd-4 on chromosome 17.

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Year:  1991        PMID： 1675432     DOI： 10.1038/351542a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  138 in total

1.  Age and sex based genetic locus heterogeneity in type 1 diabetes.

Authors:  A D Paterson; A Petronis
Journal:  J Med Genet       Date:  2000-03       Impact factor: 6.318

2.  Mapping baroreceptor function to genome: a mathematical modeling approach.

Authors:  C M Kendziorski; A W Cowley; A S Greene; H C Salgado; H J Jacob; P J Tonellato
Journal:  Genetics       Date:  2002-04       Impact factor: 4.562

3.  One hundred years of mouse genetics: an intellectual history. II. The molecular revolution (1981-2002).

Authors:  Kenneth Paigen
Journal:  Genetics       Date:  2003-04       Impact factor: 4.562

4.  Gene-expression profiling of experimental autoimmune encephalomyelitis.

Authors:  Eilhard Mix; Jens Pahnke; Saleh M Ibrahim
Journal:  Neurochem Res       Date:  2002-10       Impact factor: 3.996

5.  Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice.

Authors:  K J Buck; P Metten; J K Belknap; J C Crabbe
Journal:  J Neurosci       Date:  1997-05-15       Impact factor: 6.167

Review 6.  Molecular aspects of type 1 diabetes.

Authors:  M A Kelly; M L Rayner; C H Mijovic; A H Barnett
Journal:  Mol Pathol       Date:  2003-02

7.  Mapping genes in the mouse using single-strand conformation polymorphism analysis of recombinant inbred strains and interspecific crosses.

Authors:  D R Beier; H Dushkin; D J Sussman
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-01       Impact factor: 11.205

Review 8.  The non obese diabetic (NOD) mouse: a unique model for understanding the interaction between genetics and T cell responses.

Authors:  William M Ridgway
Journal:  Rev Endocr Metab Disord       Date:  2003-09       Impact factor: 6.514

9.  Genetic analysis of resistance to Type-1 Diabetes in ALR/Lt mice, a NOD-related strain with defenses against autoimmune-mediated diabetogenic stress.

Authors:  Clayton E Mathews; Robert T Graser; Rebecca J Bagley; Jason W Caldwell; Renhua Li; Gary A Churchill; David V Serreze; Edward H Leiter
Journal:  Immunogenetics       Date:  2003-09-25       Impact factor: 2.846

Review 10.  Mapping the mouse genome: current status and future prospects.

Authors:  W F Dietrich; N G Copeland; D J Gilbert; J C Miller; N A Jenkins; E S Lander
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-21       Impact factor: 11.205
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