OBJECTIVES: The aim of this study was to investigate the clinicoradiologic features, microbiologic data, primary sites of infection, and treatment results for patients with septic pulmonary embolism (SPE) in Korea. METHODS: We retrospectively analyzed 21 SPE patients including "definite" and "probable" cases. RESULTS: On CT scan, peripheral nodules were the most common lesions (89.0%), followed by non-nodular infiltrates (7.0%) and wedge-shaped peripheral lesions (3.2%). Cavitation and feeding vessel sign, more specific to SPE were identified in 10.4% and 6% of all the lesions, respectively. Transthoracic echocardiography revealed significant abnormalities in three of 13 patients with an additional finding of vegetation in only one of five patients when studied by transesophageal echocardiography. In 15 patients, primary sites of infection were found, and three causative organisms were isolated in 16: K. pneumoniae (8); S. aureus (6); and viridans streptococci (2). All patients received parenteral antimicrobial therapy with or without drainage of the extrapulmonary infection and 18 recovered. CONCLUSIONS: Although the pathogens of SPE may differ depending on the primary foci of infection, early diagnosis and prompt antimicrobial therapy with radiologic or surgical intervention can lead to a successful treatment outcome.
OBJECTIVES: The aim of this study was to investigate the clinicoradiologic features, microbiologic data, primary sites of infection, and treatment results for patients with septic pulmonary embolism (SPE) in Korea. METHODS: We retrospectively analyzed 21 SPE patients including "definite" and "probable" cases. RESULTS: On CT scan, peripheral nodules were the most common lesions (89.0%), followed by non-nodular infiltrates (7.0%) and wedge-shaped peripheral lesions (3.2%). Cavitation and feeding vessel sign, more specific to SPE were identified in 10.4% and 6% of all the lesions, respectively. Transthoracic echocardiography revealed significant abnormalities in three of 13 patients with an additional finding of vegetation in only one of five patients when studied by transesophageal echocardiography. In 15 patients, primary sites of infection were found, and three causative organisms were isolated in 16: K. pneumoniae (8); S. aureus (6); and viridans streptococci (2). All patients received parenteral antimicrobial therapy with or without drainage of the extrapulmonary infection and 18 recovered. CONCLUSIONS: Although the pathogens of SPE may differ depending on the primary foci of infection, early diagnosis and prompt antimicrobial therapy with radiologic or surgical intervention can lead to a successful treatment outcome.
Authors: S Ronkainen; Y Xie; M Battiwalla; A J Barrett; F Stock; J P Dekker; R L Danner Journal: Transpl Infect Dis Date: 2014-06-26 Impact factor: 2.228
Authors: Lidia Santarpia; Giulio Viceconte; Maria Foggia; Lucia Alfonsi; Grazia Tosone; Luigi Camera; Maria Carmen Pagano; Giuseppe De Simone; Franco Contaldo; Fabrizio Pasanisi Journal: Nutrients Date: 2019-03-09 Impact factor: 5.717