| Literature DB >> 16750547 |
Anita Horváth1, Rita Skoda-Földes, Sándor Mahó, Zoltán Berente, László Kollár.
Abstract
Efficient ring opening of steroidal 2,3-epoxides with stoichiometric amount of aromatic amines has been carried out using an ionic liquid ([bmim](+)[BF(4)](-)) both as solvent and catalyst. The reactions were completely regio- and stereoselective in each case. The aminoalcohol products have chair conformations in ring A. The ionic liquid-mediated ring opening can efficiently be carried out with aliphatic amines like morpholine as well.Entities:
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Year: 2006 PMID： 16750547 DOI： 10.1016/j.steroids.2006.04.006
Source DB: PubMed Journal: Steroids ISSN： 0039-128X Impact factor: 2.668