| Literature DB >> 16750416 |
Dimitris Tousoulis1, Charalambos Antoniades, Nikolaos Koumallos, Christodoulos Stefanadis.
Abstract
Cytokines are produced in a variety of tissues and regulate the expression of a number of inflammatory molecules, leading to destabilization and finally rupture of vulnerable atheromatic plaques. They also participate in the pathophysiology of acute coronary syndromes (ACS) by direct effects on myocardial contractility and apoptosis. At a clinical level, circulating cytokines have a prognostic role since they are useful markers predicting future coronary events in patients with advanced atherosclerosis and in patients after ACS.Entities:
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Year: 2006 PMID： 16750416 DOI： 10.1016/j.cytogfr.2006.04.003
Source DB: PubMed Journal: Cytokine Growth Factor Rev ISSN： 1359-6101 Impact factor: 7.638