Literature DB >> 16750369

A genetic basis for human susceptibility to West Nile virus.

Michael S Diamond1, Robyn S Klein.   

Abstract

West Nile virus (WNV) infects thousands of humans annually and causes a spectrum of disease ranging from an acute febrile illness to lethal encephalitis. A new study suggests a link between CCR5Delta32 (a common mutant allele of the chemokine and HIV receptor CCR5) and fatal WNV infection. The study highlights a possible risk in targeting this receptor for the prevention and/or treatment of infectious diseases.

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Year:  2006        PMID： 16750369     DOI： 10.1016/j.tim.2006.05.004

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  15 in total

1.  Double-edged genetic swords and immunity: lesson from CCR5 and beyond.

Authors:  Sunil K Ahuja; Weijing He
Journal:  J Infect Dis       Date:  2010-01-15       Impact factor: 5.226

2.  Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fcgamma receptor and complement-dependent effector mechanisms.

Authors:  Matthew R Vogt; Kimberly A Dowd; Michael Engle; Robert B Tesh; Syd Johnson; Theodore C Pierson; Michael S Diamond
Journal:  J Virol       Date:  2011-09-14       Impact factor: 5.103

3.  A plant-produced vaccine protects mice against lethal West Nile virus infection without enhancing Zika or dengue virus infectivity.

Authors:  Huafang Lai; Amber M Paul; Haiyan Sun; Junyun He; Ming Yang; Fengwei Bai; Qiang Chen
Journal:  Vaccine       Date:  2018-02-26       Impact factor: 3.641

4.  Access to nectin favors herpes simplex virus infection at the apical surface of polarized human epithelial cells.

Authors:  Benjamin Galen; Natalia Cheshenko; Ana Tuyama; Bharat Ramratnam; Betsy C Herold
Journal:  J Virol       Date:  2006-09-27       Impact factor: 5.103

5.  Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice.

Authors:  Huafang Lai; Michael Engle; Anja Fuchs; Thomas Keller; Syd Johnson; Sergey Gorlatov; Michael S Diamond; Qiang Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-01       Impact factor: 11.205

6.  An analogue of AICAR with dual inhibitory activity against WNV and HCV NTPase/helicase: synthesis and in vitro screening of 4-carbamoyl-5-(4,6-diamino-2,5-dihydro-1,3,5-triazin-2-yl)imidazole-1-beta-D-ribofuranoside.

Authors:  Ravi K Ujjinamatada; Andrea Baier; Peter Borowski; Ramachandra S Hosmane
Journal:  Bioorg Med Chem Lett       Date:  2007-01-27       Impact factor: 2.823

7.  Human monoclonal antibodies against West Nile virus induced by natural infection neutralize at a postattachment step.

Authors:  Matthew R Vogt; Bastiaan Moesker; Jaap Goudsmit; Mandy Jongeneelen; S Kyle Austin; Theodore Oliphant; Steevenson Nelson; Theodore C Pierson; Jan Wilschut; Mark Throsby; Michael S Diamond
Journal:  J Virol       Date:  2009-04-22       Impact factor: 5.103

8.  Fas ligand interactions contribute to CD8+ T-cell-mediated control of West Nile virus infection in the central nervous system.

Authors:  Bimmi Shrestha; Michael S Diamond
Journal:  J Virol       Date:  2007-09-05       Impact factor: 5.103

9.  A West Nile virus DNA vaccine induces neutralizing antibody in healthy adults during a phase 1 clinical trial.

Authors:  Julie E Martin; Theodore C Pierson; Sarah Hubka; Steve Rucker; Ingelise J Gordon; Mary E Enama; Charla A Andrews; Qing Xu; Brent S Davis; Martha Nason; Michael Fay; Richard A Koup; Mario Roederer; Robert T Bailer; Phillip L Gomez; John R Mascola; Gwong-Jen J Chang; Gary J Nabel; Barney S Graham
Journal:  J Infect Dis       Date:  2007-12-15       Impact factor: 5.226

10.  Chemical and biological effects of substitution of the 2-position of ring-expanded ('fat') nucleosides containing the imidazo[4,5-e][1,3]diazepine-4,8-dione ring system: the role of electronic and steric factors on glycosidic bond stability and anti-HCV activity.

Authors:  Peng Zhang; Ning Zhang; Victor E Buckwold; Ramachandra S Hosmane
Journal:  Bioorg Med Chem       Date:  2007-04-29       Impact factor: 3.641
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