| Literature DB >> 16749895 |
Donald H Rubin1, H Earl Ruley.
Abstract
Viruses are obligate intracellular parasites that rely upon the host cell for activities essential to their life cycles. Gene-trap mutagenesis provides a rapid, genome-wide strategy to identify candidate cellular genes required for virus replication. The candidate genes provide a starting point for mechanistic studies of cellular processes that participate in the virus life cycle and may provide targets for novel antiviral therapies.Entities:
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Year: 2006 PMID： 16749895 DOI： 10.1615/critreveukargeneexpr.v16.i2.40
Source DB: PubMed Journal: Crit Rev Eukaryot Gene Expr ISSN： 1045-4403 Impact factor: 1.807