Literature DB >> 16749542

Cause and motivation in cases of non-fatal drug overdoses in opiate addicts.

R Pfab1, F Eyer, E Jetzinger, Thomas Zilker.   

Abstract

INTRODUCTION: Drug overdose (OD) is a frequent incident among opiate addicts. Survivors of ODs are at risk for additional and eventually fatal ODs. ODs may be classified as accidental (aOD) or deliberate (dOD). Investigations into the connection between OD and suicide attempts have led to insconsistent results.
PURPOSE: (1) to determine how many non-fatal ODs were dODs and how many were aODs; (2) to determine how many cases of dODs were motivated by explicit or by ambivalent suicidal intentions; (3) to determine how many cases of aODs had causes that might respond to preventative measures; (4) to compare the addiction histories of dODs and aODs; (5) to compare the drugs causing the ODs; and (6) to compare the severity of the ODs in both groups.
METHODS: Prospective study utilizing a standardized questionnaire to evaluate opiate-addicted patients admitted to our treatment unit for OD. All cases underwent standardized drug testing to identify drug use patterns.
RESULTS: Seventy-four cases of OD underwent standardized interviews after awakening. Forty-three percent of the cases were dOD. Cases of dOD had significantly more OA in substitution programs, more previous ODs, and more often consumed methadone and cocaine. Among dODs, 22.5% had suicidal intention and 9.6% were ambivalent about committing suicide; background motivations were most often conflicts with spouses. Fifty-seven percent of the cases were aOD. Cases of aODs had significantly more potential lethal intoxications and had heroin detected more frequently. aODs happened with unexpected pure heroin (46%), in combination with alcohol (36%), as relapse after abstinence (40%) or after institutionalized treatment (19%). This group should be accessible for targeted education.

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Year:  2006        PMID: 16749542     DOI: 10.1080/15563650600584394

Source DB:  PubMed          Journal:  Clin Toxicol (Phila)        ISSN: 1556-3650            Impact factor:   4.467


  10 in total

1.  A procedure that differentiates unintentional from intentional overdose in opioid abusers.

Authors:  Peter C Britton; Amy S B Bohnert; James D Wines; Kenneth R Conner
Journal:  Addict Behav       Date:  2011-09-02       Impact factor: 3.913

2.  Concurrent Alcohol and Opioid Use Among Harm Reduction Clients.

Authors:  Erin L Winstanley; Amanda N Stover; Judith Feinberg
Journal:  Addict Behav       Date:  2019-06-20       Impact factor: 3.913

3.  Fatal poisonings in Oslo: a one-year observational study.

Authors:  Mari A Bjornaas; Brita Teige; Knut E Hovda; Oivind Ekeberg; Fridtjof Heyerdahl; Dag Jacobsen
Journal:  BMC Emerg Med       Date:  2010-06-06

4.  Preventing death among the recently incarcerated: an argument for naloxone prescription before release.

Authors:  Sarah E Wakeman; Sarah E Bowman; Michelle McKenzie; Alexandra Jeronimo; Josiah D Rich
Journal:  J Addict Dis       Date:  2009

5.  Nonmedical Opioid Use in Relation to Recency of Heroin Use in a Nationally Representative Sample of Adults in the United States.

Authors:  Joseph J Palamar; Jenni A Shearston
Journal:  J Psychoactive Drugs       Date:  2017-09-12

6.  The role of depression and social support in non-fatal drug overdose among a cohort of injection drug users in a Canadian setting.

Authors:  Roman Pabayo; Carmela Alcantara; Ichiro Kawachi; Evan Wood; Thomas Kerr
Journal:  Drug Alcohol Depend       Date:  2013-05-04       Impact factor: 4.492

7.  Suicidal intention, psychosocial factors and referral to further treatment: a one-year cross-sectional study of self-poisoning.

Authors:  Mari A Bjornaas; Knut E Hovda; Fridtjof Heyerdahl; Karina Skog; Per Drottning; Anders Opdahl; Dag Jacobsen; Oivind Ekeberg
Journal:  BMC Psychiatry       Date:  2010-07-26       Impact factor: 3.630

Review 8.  Epidemiology of Suicide and the Psychiatric Perspective.

Authors:  Silke Bachmann
Journal:  Int J Environ Res Public Health       Date:  2018-07-06       Impact factor: 3.390

9.  A 20-year prospective study of mortality and causes of death among hospitalized opioid addicts in Oslo.

Authors:  Mari A Bjornaas; Anette S Bekken; Aasa Ojlert; Tor Haldorsen; Dag Jacobsen; Morten Rostrup; Oivind Ekeberg
Journal:  BMC Psychiatry       Date:  2008-02-13       Impact factor: 3.630

10.  Five-year mortality after acute poisoning treated in ambulances, an emergency outpatient clinic and hospitals in Oslo.

Authors:  Cathrine Lund; Mari A Bjornaas; Leiv Sandvik; Oivind Ekeberg; Dag Jacobsen; Knut E Hovda
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2013-08-21       Impact factor: 2.953

  10 in total

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