Literature DB >> 1674869

Primary structure of mouse tyrosine hydroxylase deduced from its cDNA.

S Ichikawa1, T Sasaoka, T Nagatsu.   

Abstract

The cDNAs for tyrosine hydroxylase were cloned from a mouse brain cDNA library by plaque hybridization. Since the longest cDNA clone lacked approximately 150 bp sequence of its N-terminal region, additional 5' region was obtained using polymerase chain reaction. Nucleotide sequence determination of cDNAs revealed that mouse tyrosine hydroxylase m-RNA encodes 498 amino acids with a calculated molecular mass of 55,990. The amino acid sequence of mouse tyrosine hydroxylase is highly homologous to rat (97%) and human (92%) enzymes.

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Year:  1991        PMID： 1674869     DOI： 10.1016/0006-291x(91)90472-j

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  11 in total

1.  VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity.

Authors:  N Takahashi; L L Miner; I Sora; H Ujike; R S Revay; V Kostic; V Jackson-Lewis; S Przedborski; G R Uhl
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-02       Impact factor: 11.205

2.  Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase.

Authors:  M Rios; B Habecker; T Sasaoka; G Eisenhofer; H Tian; S Landis; D Chikaraishi; S Roffler-Tarlov
Journal:  J Neurosci       Date:  1999-05-01       Impact factor: 6.167

3.  Cloning and characterization of a novel enzyme: tyrosine hydroxylase from Schistosoma japonicum.

Authors:  Yuansheng Hu; Dujuan Shi; Qingli Luo; Qingzhong Liu; Yindi Zhou; Lili Liu; Li Yu; Wei Wei; Jilong Shen
Journal:  Parasitol Res       Date:  2011-05-10       Impact factor: 2.289

4.  Generation of tyrosine hydroxylase-producing neurons from precursors of the embryonic and adult forebrain.

Authors:  M M Daadi; S Weiss
Journal:  J Neurosci       Date:  1999-06-01       Impact factor: 6.167

5.  Regulation of N-terminus-deleted human tyrosine hydroxylase type 1 by end products of catecholamine biosynthetic pathway.

Authors:  A Ota; S Yoshida; T Nagatsu
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575

Review 6.  Tyrosine hydroxylase (TH), its cofactor tetrahydrobiopterin (BH4), other catecholamine-related enzymes, and their human genes in relation to the drug and gene therapies of Parkinson's disease (PD): historical overview and future prospects.

Authors:  Toshiharu Nagatsu; Ikuko Nagatsu
Journal:  J Neural Transm (Vienna)       Date:  2016-08-04       Impact factor: 3.575

7.  Expression of human tyrosine hydroxylase-chloramphenicol acetyltransferase (CAT) fusion gene in the brains of transgenic mice as examined by CAT immunocytochemistry.

Authors:  I Nagatsu; N Karasawa; K Yamada; M Sakai; T Fujii; T Takeuchi; R Arai; K Kobayashi; T Nagatsu
Journal:  J Neural Transm Gen Sect       Date:  1994

8.  Effects of subacute administration of methamphetamine and nicotine on locomotor activity in transgenic mice expressing the human tyrosine hydroxylase gene.

Authors:  T Nabeshima; A Itoh; K Kobayashi; S Morita; T Mizuguchi; H Sawada; A Nitta; T Hasegawa; K Hayashi; T Nagatsu
Journal:  J Neural Transm Gen Sect       Date:  1994

Review 9.  Human tyrosine hydroxylase in Parkinson's disease and in related disorders.

Authors:  Toshiharu Nagatsu; Akira Nakashima; Hiroshi Ichinose; Kazuto Kobayashi
Journal:  J Neural Transm (Vienna)       Date:  2018-07-11       Impact factor: 3.575

10.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1991-09-11       Impact factor: 16.971
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