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Literature DB >> 16742575

Effect of virus infection on the stability and synthesis of actinomycin-resistant ribonucleic acid in baby-hamster kidney cells.

Abstract

1. The sucrose-gradient pattern of (32)P-labelled RNA synthesized in actinomycintreated baby-hamster kidney cells infected with foot-and-mouth-disease virus depends greatly on the period of labelling. 2. Fractions are formed in infected cells that sediment at 12-20s and have the same base composition as similar fractions found in non-infected cells that have been treated with actinomycin. 3. In the presence of guanidine, which completely inhibits viral RNA synthesis, these fractions are labelled to a greater extent than in non-infected cells.

Entities: Chemical Disease Species

Year: 1967 PMID： 16742575 PMCID： PMC1198417 DOI： 10.1042/bj1050987

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

13 in total

1. INHIBITION OF HOST CELL MACROMOLECULAR SYNTHESIS BY HIGH MULTIPLICITIES OF POLIOVIRUS UNDER CONDITIONS PREVENTING VIRUS SYNTHESIS.

Authors: J J HOLLAND
Journal: J Mol Biol Date: 1964-04 Impact factor: 5.469

2. INHIBITION OF MULTIPLICATION OF FOOT-AND-MOUTH DISEASE VIRUS BY GUANIDINE HYDROCHLORIDE.

Authors: C R PRINGLE
Journal: Nature Date: 1964-12-05 Impact factor: 49.962

3. THE REPLICATION OF BACTERIOPHAGE MS2. IV. RNA COMPONENTS SPECIFICALLY ASSOCIATED WITH INFECTION.

Authors: R B KELLY; J L GOULD; R L SINSHEIMER
Journal: J Mol Biol Date: 1965-03 Impact factor: 5.469

4. STUDIES ON THE MECHANISM OF POLIOVIRUS-INDUCED CELL DAMAGE. I. THE RELATION BETWEEN POLIOVIRUS,-INDUCED METABOLIC AND MORPHOLOGICAL ALTERATIONS IN CULTURED CELLS.

Authors: R BABLANIAN; H J EGGERS; I TAMM
Journal: Virology Date: 1965-05 Impact factor: 3.616

Effect of virus infection on the stability and synthesis of actinomycin-resistant ribonucleic acid in baby-hamster kidney cells.

1. INHIBITION OF HOST CELL MACROMOLECULAR SYNTHESIS BY HIGH MULTIPLICITIES OF POLIOVIRUS UNDER CONDITIONS PREVENTING VIRUS SYNTHESIS.

2. INHIBITION OF MULTIPLICATION OF FOOT-AND-MOUTH DISEASE VIRUS BY GUANIDINE HYDROCHLORIDE.

3. THE REPLICATION OF BACTERIOPHAGE MS2. IV. RNA COMPONENTS SPECIFICALLY ASSOCIATED WITH INFECTION.

4. STUDIES ON THE MECHANISM OF POLIOVIRUS-INDUCED CELL DAMAGE. I. THE RELATION BETWEEN POLIOVIRUS,-INDUCED METABOLIC AND MORPHOLOGICAL ALTERATIONS IN CULTURED CELLS.

5. Patterns of macromolecular synthesis in normal and virus-infected mammalian cells.

6. A study of the kinetics of protein and RNA synthesis induced by foot-and-mouth disease virus.

7. The mechanism of host cell protein synthesis inhibition by poliovirus.

8. Heterogeneous RNA's occurring during the replication of Western equine encephalomyelitis virus.

9. Effects on host cell metabolism following synchronous infection with poliovirus.

10. A new model for virus ribonucleic acid replication.

1. Synthesis of ribonucleic acid in baby-hamster kidney cells in the presence of actinomycin D.