Upper gastrointestinal bleeding in a patient with AIDS.

BACKGROUND: A 38-year-old man with AIDS and hepatitis C was admitted to our hospital in January 2005, with complaints of epigastric pain, odynophagia, and melena of 4 days' duration. The patient was not taking highly active antiretroviral therapy because of poor compliance and he denied use of NSAIDs. INVESTIGATIONS: Physical examination, stool guaiac test, laboratory investigations, and esophagogastroduodenoscopy with biopsies of gastric ulcerations. DIAGNOSIS: Non-Hodgkin's lymphoma of the stomach (diffuse large B-cell type) with associated gastric ulceration and bleeding. MANAGEMENT: Injection of epinephrine and bipolar coagulation for the bleeding malignant ulcer, and PPI therapy.