Literature DB >> 16740741

The signaling and biological implications of FAK overexpression in cancer.

Priscila M F Siesser1, Steven K Hanks.   

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Year:  2006        PMID： 16740741     DOI： 10.1158/1078-0432.CCR-06-0456

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


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  82 in total

1.  PTEN Expression as a Predictor of Response to Focal Adhesion Kinase Inhibition in Uterine Cancer.

Authors:  Duangmani Thanapprapasr; Rebecca A Previs; Wei Hu; Cristina Ivan; Guillermo N Armaiz-Pena; Piotr L Dorniak; Jean M Hansen; Rajesha Rupaimoole; Jie Huang; Heather J Dalton; Rouba Ali-Fehmi; Robert L Coleman; Anil K Sood
Journal:  Mol Cancer Ther       Date:  2015-04-01       Impact factor: 6.261

2.  Oncogenic Receptor Tyrosine Kinases Directly Phosphorylate Focal Adhesion Kinase (FAK) as a Resistance Mechanism to FAK-Kinase Inhibitors.

Authors:  Timothy A Marlowe; Felicia L Lenzo; Sheila A Figel; Abigail T Grapes; William G Cance
Journal:  Mol Cancer Ther       Date:  2016-09-16       Impact factor: 6.261

3.  Nuclear FAK and Runx1 Cooperate to Regulate IGFBP3, Cell-Cycle Progression, and Tumor Growth.

Authors:  Marta Canel; Adam Byron; Andrew H Sims; Jessy Cartier; Hitesh Patel; Margaret C Frame; Valerie G Brunton; Bryan Serrels; Alan Serrels
Journal:  Cancer Res       Date:  2017-08-14       Impact factor: 12.701

4.  Design, synthesis, and biological evaluation of novel FAK scaffold inhibitors targeting the FAK-VEGFR3 protein-protein interaction.

Authors:  Priyanka N Gogate; Manivannan Ethirajan; Elena V Kurenova; Andrew T Magis; Ravindra K Pandey; William G Cance
Journal:  Eur J Med Chem       Date:  2014-04-15       Impact factor: 6.514

5.  AMPA receptors promote perivascular glioma invasion via beta1 integrin-dependent adhesion to the extracellular matrix.

Authors:  Yuji Piao; Li Lu; John de Groot
Journal:  Neuro Oncol       Date:  2008-10-28       Impact factor: 12.300

6.  Function of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivo.

Authors:  Huaping Fan; Xiaofeng Zhao; Shaogang Sun; Ming Luo; Jun-Lin Guan
Journal:  J Biol Chem       Date:  2012-12-19       Impact factor: 5.157

7.  Therapeutic Potential of Focal Adhesion Kinase Inhibition in Small Cell Lung Cancer.

Authors:  Frank Aboubakar Nana; Marylène Lecocq; Maha Zohra Ladjemi; Bruno Detry; Sébastien Dupasquier; Olivier Feron; Pierre P Massion; Yves Sibille; Charles Pilette; Sebahat Ocak
Journal:  Mol Cancer Ther       Date:  2018-10-23       Impact factor: 6.261

Review 8.  Disrupting the scaffold to improve focal adhesion kinase-targeted cancer therapeutics.

Authors:  William G Cance; Elena Kurenova; Timothy Marlowe; Vita Golubovskaya
Journal:  Sci Signal       Date:  2013-03-26       Impact factor: 8.192

9.  Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion.

Authors:  X N Meng; Y Jin; Y Yu; J Bai; G Y Liu; J Zhu; Y Z Zhao; Z Wang; F Chen; K-Y Lee; S B Fu
Journal:  Br J Cancer       Date:  2009-06-30       Impact factor: 7.640

10.  Role of kinase-independent and -dependent functions of FAK in endothelial cell survival and barrier function during embryonic development.

Authors:  Xiaofeng Zhao; Xu Peng; Shaogang Sun; Ann Y J Park; Jun-Lin Guan
Journal:  J Cell Biol       Date:  2010-06-07       Impact factor: 10.539
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