Literature DB >> 16740282

Laurentixanthones A and B, antimicrobial xanthones from Vismia laurentii.

Jean Robert Nguemeving1, Anatole Guy Blaise Azebaze, Victor Kuete, Nono Nono Eric Carly, Véronique Penlap Beng, Michèle Meyer, Alain Blond, Bernard Bodo, Augustin Ephrem Nkengfack.   

Abstract

A phytochemical investigation of the constituents of the roots of Vismia laurentii has resulted in the isolation of two xanthone derivatives named laurentixanthone A (1) (6-hydroxy-3,3-dimethyl-11-(3-methylbut-2-enyl)pyrano[2,3-c]xanthen-7(3H)-one) and laurentixanthone B (2) (1-hydroxy-5,6,7,8-tetramethoxyxanthone), along with 11 known compounds: 1,7-dihydroxyxanthone, vismiaquinone, vismiaquinone B, bivismiaquinone, 3-geranyloxy-6-methyl-1,8-dihydroxyanthraquinone, O(1)-demethyl-3',4'-deoxypsorospermin-3',4'-diol, 6-deoxyisojacareubin, 1,8-dihydroxy-6-methoxy-3-methylanthraquinone, kaempferol, friedelin and stigmasterol. The structures of compounds were established by means of spectroscopic methods. Furthermore, the compounds were screened for antimicrobial activities in vitro.

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Year:  2006        PMID: 16740282     DOI: 10.1016/j.phytochem.2006.03.018

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  11 in total

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10.  Anticancer and antimicrobial activities of some antioxidant-rich cameroonian medicinal plants.

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