| Literature DB >> 1673740 |
T Aya1, T Kinoshita, S Imai, S Koizumi, F Mizuno, T Osato, C Satoh, T Oikawa, N Kuzumaki, H Ohigashi.
Abstract
Dual exposure to Epstein-Barr virus and purified 4-deoxyphorbol ester derived from the plant Euphorbia tirucalli induced a high frequency of chromosomal rearrangements in human B lymphocytes in vitro. Rearrangements most commonly affected chromosome 8, the chromosome most often showing structural changes in Burkitt's lymphoma (BL) cells. E tirucalli is indigenous in parts of Africa where BL is endemic and may be an important risk factor for the disease.Entities:
Mesh：
Substances：
Year: 1991 PMID： 1673740 DOI： 10.1016/0140-6736(91)92861-u
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321