Literature DB >> 16735982

Evaluation of the thyroid nodule.

Christopher D Lansford1, Theodoros N Teknos.   

Abstract

BACKGROUND: Thyroid nodules are common, yet treatment modalities range from observation to surgical resection. Because thyroid nodules are frequently found incidentally during routine physical examination or imaging performed for another reason, physicians from a diverse range of specialties encounter thyroid nodules. Clinical decision making depends on proper evaluation of the thyroid nodule.
METHODS: The current literature was reviewed and synthesized.
RESULTS: Current evidence allows the formulation of recommendations and a general algorithm for evaluating the incidental thyroid nodule.
CONCLUSIONS: Only a small percentage of thyroid nodules require surgical management. Diagnosis and treatment selection require a risk stratification by history, physical examination, and ancillary tests. Nodules causing airway compression or those at high risk for carcinoma should prompt evaluation for surgical treatment. In nodules larger than 1 cm, fine-needle aspiration biopsy is central to the evaluation as it is accurate, low risk, and cost effective. Subcentimeter nodules, often found incidentally on imaging obtained for another purpose, can usually be evaluated by ultrasonography. Other laboratory and imaging evaluations have specific and more limited roles. An algorithm for the evaluation of the thyroid nodule is presented.

Entities:  

Mesh:

Year:  2006        PMID: 16735982     DOI: 10.1177/107327480601300202

Source DB:  PubMed          Journal:  Cancer Control        ISSN: 1073-2748            Impact factor:   3.302


  15 in total

1.  VEGF and GM-CSF levels in nodular thyroid diseases.

Authors:  Birsen Bilgici; Gulcin C Ecemis; Ozgur K Tuncel; Ilkay K Bayrak; Elif K Kan; Aysegul Atmaca
Journal:  Endocrine       Date:  2013-04-28       Impact factor: 3.633

2.  HSA-MnO2-131I Combined Imaging and Treatment of Anaplastic Thyroid Carcinoma.

Authors:  Ziyu Yan; Xuemei Zhang; Yifan Liu; Yiming Shen; Ning Li; Qiang Jia; Yanhui Ji; Peitao Zhang; Li Zhao; Zhaowei Meng
Journal:  Technol Cancer Res Treat       Date:  2022 Jan-Dec

3.  Contrast-Enhanced Ultrasonography for Differential Diagnosis of Benign and Malignant Thyroid Lesions: Single-Institutional Prospective Study of Qualitative and Quantitative CEUS Characteristics.

Authors:  Hana Petrasova; Radka Slaisova; Tomas Rohan; Karel Stary; Jitka Kyclova; Tomas Pavlik; Petra Kovalcikova; Tomas Kazda; Vlastimil Valek
Journal:  Contrast Media Mol Imaging       Date:  2022-04-23       Impact factor: 3.009

Review 4.  Management of Thyroid nodules in adult patients.

Authors:  Chee Yean Eng; Muhammad S Quraishi; Patrick J Bradley
Journal:  Head Neck Oncol       Date:  2010-05-05

5.  Accuracy of fine-needle aspiration biopsy for predicting neoplasm or carcinoma in thyroid nodules 4 cm or larger.

Authors:  Scott N Pinchot; Hatem Al-Wagih; Sarah Schaefer; Rebecca Sippel; Herbert Chen
Journal:  Arch Surg       Date:  2009-07

6.  TSH alone is not sufficient to exclude all patients with a functioning thyroid nodule from undergoing testing to exclude thyroid cancer.

Authors:  Luis-Mauricio Hurtado-López; Blanca-Estela Monroy-Lozano; Carlos Martínez-Duncker
Journal:  Eur J Nucl Med Mol Imaging       Date:  2008-01-04       Impact factor: 9.236

7.  Thyroid nodules in childhood: a single institute experience.

Authors:  Alireza Mirshemirani; Fatolah Roshanzamir; Ahmad Khaleghnejad Tabari; Javad Ghorobi; Shadab Salehpoor; Fatemeh Abdollah Gorji
Journal:  Iran J Pediatr       Date:  2010-03       Impact factor: 0.364

8.  Integrative metabonomics as potential method for diagnosis of thyroid malignancy.

Authors:  Yuan Tian; Xiu Nie; Shan Xu; Yan Li; Tao Huang; Huiru Tang; Yulan Wang
Journal:  Sci Rep       Date:  2015-10-21       Impact factor: 4.379

9.  Predictors of a follicular nodule (Thy3) outcome of thyroid fine needle aspiration cytology among Saudi patients.

Authors:  Imad R Musa; Mukhtar El Khatim Ahmad; Fayez Salim Al Raddady; Wesal Rabih Al Rabih; Elsayed M Elsayed; Gussay Badawi Mohamed; Gasim I Gasim
Journal:  BMC Res Notes       Date:  2017-11-23

Review 10.  Thyroid nodule management: clinical, ultrasound and cytopathological parameters for predicting malignancy.

Authors:  Frederico F R Maia; Denise Engelbrecht Zantut-Wittmann
Journal:  Clinics (Sao Paulo)       Date:  2012-08       Impact factor: 2.365

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