| Literature DB >> 16735123 |
Andrzej B Hendrich1, Kamila Stańczak, Małgorzata Komorowska, Noboru Motohashi, Masami Kawase, Krystyna Michalak.
Abstract
The interactions of six newly synthesized phenoxazine derivatives with lipid bilayers were studied by means of calorimetry, fluorescence spectroscopic methods and electron spin resonance. Depending on their structure studied compounds decreased membrane fluidity and increased lipid order in liquid-crystalline bilayers to different degrees. These studies showed also that phenoxazine molecules are located close to the polar/apolar interface of bilayer. The results allow to conclude that phenoxazines rather weakly interact with lipid bilayers.Entities:
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Year: 2006 PMID： 16735123 DOI： 10.1016/j.bmc.2006.05.021
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641