| Literature DB >> 1673487 |
E Duchayne1, G Delsol, E Kuhlein, B Klein, X G Zhang, M Attal, G Cassard, G Laurent.
Abstract
The normal counterparts of the B cells found in hairy cell leukemia (HCL) are not known. We report here a detailed morphological, cytochemical, immunological and molecular analysis of a patient with B-cell chronic lymphocytic leukemia (B-CLL) who later in the course of his disease developed hairy cell leukemia. We speculate that hairy cell transformation of B-CLL might be related to an in vivo protein kinase C mediated cellular activation of B-CLL cells.Entities:
Mesh:
Substances:
Year: 1991 PMID: 1673487
Source DB: PubMed Journal: Leukemia ISSN: 0887-6924 Impact factor: 11.528