Literature DB >> 16734691

Refinement of quantitative trait loci on bovine chromosome 18 affecting health and reproduction in US Holsteins.

S A Muncie1, J P Cassady, M S Ashwell.   

Abstract

Selection for increased milk yield is associated with decreased fertility in US Holsteins. Previously, a putative quantitative trait locus (QTL) on chromosome 18 affecting daughter pregnancy rate (DPR) was identified in one family. Our aim was to determine the validity of the QTL using additional markers and an extended pedigree. Twelve markers were genotyped in 940 descendants of the original sire in which the QTL was identified. Analysis of the extended pedigree detected significant and suggestive QTL for DPR, productive life and somatic cell score. Further analysis is underway to refine the QTL region so that positional candidate genes can be identified.

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Year:  2006        PMID: 16734691     DOI: 10.1111/j.1365-2052.2006.01425.x

Source DB:  PubMed          Journal:  Anim Genet        ISSN: 0268-9146            Impact factor:   3.169


  2 in total

1.  Validation of markers with non-additive effects on milk yield and fertility in Holstein and Jersey cows.

Authors:  Hassan Aliloo; Jennie E Pryce; Oscar González-Recio; Benjamin G Cocks; Ben J Hayes
Journal:  BMC Genet       Date:  2015-07-22       Impact factor: 2.797

2.  Most parsimonious haplotype allele sharing determination.

Authors:  Zhipeng Cai; Hadi Sabaa; Yining Wang; Randy Goebel; Zhiquan Wang; Jiaofen Xu; Paul Stothard; Guohui Lin
Journal:  BMC Bioinformatics       Date:  2009-04-21       Impact factor: 3.169

  2 in total

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