INTRODUCTION: Spermatocytic seminoma is a relatively rare testicular tumour, not associated with another germ-cell tumour component and characterized by a favourable prognosis. However, discovery of a sarcomatous contingent modifies the prognosis. MATERIAL AND METHOD: The authors report the case of a 50-year-old man with a history of right testicular swelling for 4 years, gradually increasing in size without vaginal effusion. Tumour markers were normal. Ultrasound demonstrated a very large semi-solid semi-cystic testicular mass with a long axis of 14 cm. Orchidectomy was performed. RESULT: Histological examination and immunohistochemistry of the orchidectomy specimen concluded on spermatocytic seminoma associated with a rhabdomyosarcomatous component. CONCLUSION: Only 12 cases of spermatocytic seminoma with sarcomatous component have been reported in the literature The presence of a sarcomatous component confers a very poor prognosis to spermatocytic seminoma.
INTRODUCTION:Spermatocytic seminoma is a relatively rare testicular tumour, not associated with another germ-cell tumour component and characterized by a favourable prognosis. However, discovery of a sarcomatous contingent modifies the prognosis. MATERIAL AND METHOD: The authors report the case of a 50-year-old man with a history of right testicular swelling for 4 years, gradually increasing in size without vaginal effusion. Tumour markers were normal. Ultrasound demonstrated a very large semi-solid semi-cystic testicular mass with a long axis of 14 cm. Orchidectomy was performed. RESULT: Histological examination and immunohistochemistry of the orchidectomy specimen concluded on spermatocytic seminoma associated with a rhabdomyosarcomatous component. CONCLUSION: Only 12 cases of spermatocytic seminoma with sarcomatous component have been reported in the literature The presence of a sarcomatous component confers a very poor prognosis to spermatocytic seminoma.
Authors: Josias Bastian Grogg; Kym Schneider; Peter-Karl Bode; Marian Severin Wettstein; Benedikt Kranzbühler; Daniel Eberli; Tullio Sulser; Joerg Beyer; Thomas Hermanns; Christian Daniel Fankhauser Journal: J Cancer Res Clin Oncol Date: 2019-10-23 Impact factor: 4.553