Literature DB >> 16732541

Inhibitory effect of isoprenoid-substituted flavonoids isolated from Artocarpus heterophyllus on melanin biosynthesis.

Enos Tangke Arung1, Kuniyoshi Shimizu, Ryuichiro Kondo.   

Abstract

Isoprenoid-substituted flavonoids were isolated from the wood of Artocarpus heterophyllus by means of activity-guided fractionation. Artocarpin (1), cudraflavone C (2), 6-prenylapigenin (3), kuwanon C (4), norartocarpin (5) and albanin A (6) inhibited melanin biosynthesis in B16 melanoma cells without inhibiting tyrosinase. A structure-activity investigation indicated that the presence of the isoprenoid-substituted moiety enhanced the inhibitory activity on melanin production in B16 melanoma cells.

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Year:  2006        PMID： 16732541     DOI： 10.1055/s-2006-931606

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  8 in total

1.  Cytotoxic effect of artocarpin on T47D cells.

Authors:  Enos Tangke Arung; Britanto Dani Wicaksono; Yohana Ayupriyanti Handoko; Irawan Wijaya Kusuma; Kuniyoshi Shimizu; Dina Yulia; Ferry Sandra
Journal:  J Nat Med       Date:  2010-06-11       Impact factor: 2.343

Review 2.  Applications of Friedel-Crafts reactions in total synthesis of natural products.

Authors:  Majid M Heravi; Vahideh Zadsirjan; Pegah Saedi; Tayebeh Momeni
Journal:  RSC Adv       Date:  2018-12-03       Impact factor: 4.036

3.  Determination of in vitro free radical scavenging and antiproliferative effect of Pennisetum alopecuroides on cultured A549 human lung cancer cells.

Authors:  Githa Elizabeth Mathew; Bijo Mathew; S Gokul; Rahul Krishna; M P Farisa
Journal:  Anc Sci Life       Date:  2015 Jan-Mar

4.  Cudraflavone C Induces Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS Production and MAPK Activation.

Authors:  Chiang-Wen Lee; Feng-Lin Yen; Horng-Huey Ko; Shu-Yu Li; Yao-Chang Chiang; Ming-Hsueh Lee; Ming-Horng Tsai; Lee-Fen Hsu
Journal:  Int J Mol Sci       Date:  2017-07-13       Impact factor: 5.923

5.  Characterization and Identification of Prenylated Flavonoids from Artocarpus heterophyllus Lam. Roots by Quadrupole Time-Of-Flight and Linear Trap Quadrupole Orbitrap Mass Spectrometry.

Authors:  Jin-Bao Ye; Gang Ren; Wen-Yan Li; Guo-Yue Zhong; Min Zhang; Jin-Bin Yuan; Ting Lu
Journal:  Molecules       Date:  2019-12-15       Impact factor: 4.411

6.  Extracts of Artocarpus communis decrease α-melanocyte stimulating hormone-induced melanogenesis through activation of ERK and JNK signaling pathways.

Authors:  Yi-Tzu Fu; Chiang-Wen Lee; Horng-Huey Ko; Feng-Lin Yen
Journal:  ScientificWorldJournal       Date:  2014-03-05

7.  Artocarpin Induces Apoptosis in Human Cutaneous Squamous Cell Carcinoma HSC-1 Cells and Its Cytotoxic Activity Is Dependent on Protein-Nutrient Concentration.

Authors:  Stephen Chu-Sung Hu; Chi-Ling Lin; Hui-Min Cheng; Gwo-Shing Chen; Chiang-Wen Lee; Feng-Lin Yen
Journal:  Evid Based Complement Alternat Med       Date:  2015-01-14       Impact factor: 2.629

8.  Neuroprotective and Anti-Inflammatory Effects of Kuwanon C from Cudrania tricuspidata Are Mediated by Heme Oxygenase-1 in HT22 Hippocampal Cells, RAW264.7 Macrophage, and BV2 Microglia.

Authors:  Wonmin Ko; Chi-Su Yoon; Kwan-Woo Kim; Hwan Lee; Nayeon Kim; Eun-Rhan Woo; Youn-Chul Kim; Dae Gill Kang; Ho Sub Lee; Hyuncheol Oh; Dong-Sung Lee
Journal:  Int J Mol Sci       Date:  2020-07-08       Impact factor: 5.923
  8 in total

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