Literature DB >> 16731676

Post-exposure HIV prophylaxis following sexual exposure: a retrospective audit against recent draft BASHH guidance.

S Day1, A Mears, K Bond, R Kulasegaram.   

Abstract

OBJECTIVES: To retrospectively audit the management of post-exposure HIV prophylaxis following sexual exposure (PEPSE) against the British Association for Sexual Health and HIV 2004 draft guidance.
METHODS: A retrospective review of case notes from January 2000 to November 2004. The draft guidelines were not adopted into clinical practice during the study period.
RESULTS: 76 patients received PEPSE. 79% (95% CI 68.08 to 87.46) of PEPSE prescriptions were given for exposures that were in accordance with the guidelines' recommended indications (target 90%). 87% (95% CI 77.13 to 93.51) of PEPSE was prescribed within 72 hours of risk exposure (target 90%). 91% (95% CI 81.94 to 96.22) of recipients received a recommended antiretroviral combination. 53% (95% CI 40.84 to 64.21) of recipients completed the PEPSE course (target 75%). 45% of patients attended for the 3 month follow up HIV test but only 12% (95% CI 5.56 to 21.29) attended for both the 3 month and 6 month HIV test (target 75%).
CONCLUSION: PEPSE is predominantly being prescribed for recommended indications and is dispensed within 72 hours of risk exposure. PEPSE completion rates and attendance for 3 months and 6 months post-exposure HIV testing need improving, perhaps by introducing a PEPSE clinic.

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Year:  2006        PMID: 16731676      PMCID: PMC2564746          DOI: 10.1136/sti.2005.017764

Source DB:  PubMed          Journal:  Sex Transm Infect        ISSN: 1368-4973            Impact factor:   3.519


  1 in total

1.  Can the promotion of post-exposure prophylaxis following sexual exposure to HIV (PEPSE) cause harm?

Authors:  J Richens; S G Edwards; S T Sadiq
Journal:  Sex Transm Infect       Date:  2005-06       Impact factor: 3.519

  1 in total
  5 in total

1.  High Levels of Concomitant Behavioral Health Disorders Among Patients Presenting for HIV Non-occupational Post-exposure Prophylaxis at a Boston Community Health Center Between 1997 and 2013.

Authors:  Sachin Jain; Catherine E Oldenburg; Matthew J Mimiaga; Kenneth H Mayer
Journal:  AIDS Behav       Date:  2016-07

Review 2.  Preparing for HIV pre-exposure prophylaxis: lessons learned from post-exposure prophylaxis.

Authors:  Stephanie E Cohen; Albert Y Liu; Kyle T Bernstein; Susan Philip
Journal:  Am J Prev Med       Date:  2013-01       Impact factor: 5.043

Review 3.  Adherence to post-exposure prophylaxis for non-forcible sexual exposure to HIV: a systematic review and meta-analysis.

Authors:  Catherine E Oldenburg; Till Bärnighausen; Guy Harling; Matthew J Mimiaga; Kenneth H Mayer
Journal:  AIDS Behav       Date:  2014-02

Review 4.  Current perspectives in HIV post-exposure prophylaxis.

Authors:  Binta Sultan; Paul Benn; Laura Waters
Journal:  HIV AIDS (Auckl)       Date:  2014-10-24

5.  A mixed methods study of non-occupational post-exposure prophylaxis at an STI clinic in Singapore: Five-year retrospective analysis and providers' perspectives.

Authors:  Alvin Kuo Jing Teo; Bee Choo Tai; Martin Tze-Wei Chio; Hanh Hao La
Journal:  PLoS One       Date:  2018-08-20       Impact factor: 3.240

  5 in total

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