| Literature DB >> 16730983 |
Fabrizio Micheli1, Alessandra Pasquarello, Giovanna Tedesco, Dieter Hamprecht, Giorgio Bonanomi, Anna Checchia, Albert Jaxa-Chamiec, Federica Damiani, Silvia Davalli, Daniele Donati, Chiara Gallotti, Marcella Petrone, Marilisa Rinaldi, Graham Riley, Silvia Terreni, Martyn Wood.
Abstract
Within the continuous quest for the discovery of novel compounds able to treat anxiety and depression, the generation of a pharmacophore model for 5-HT2C receptor antagonists and the discovery of a new class of potent and selective 5-HT2C molecules are reported.Entities:
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Year: 2006 PMID： 16730983 DOI： 10.1016/j.bmcl.2006.05.034
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823