Literature DB >> 16730214

Hypersexuality and paraphilia induced by selegiline in Parkinson's disease: report of 2 cases.

Michael A Shapiro1, Yu Ling Chang, Sarah K Munson, Michael S Okun, Hubert H Fernandez.   

Abstract

While hypersexuality and paraphilia are known side effects of anti-Parkinson medications, it is seldom reported. Furthermore, selegiline is rarely implicated in such behaviors. We report two cases of early onset PD who experienced paraphilia and hypersexuality when selegiline was initiated, and later developing obsessive-compulsive and punding behavior with the addition of dopamine agonists. Social repercussions may prohibit patients and/or their families from volunteering such information.

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Year:  2006        PMID: 16730214     DOI: 10.1016/j.parkreldis.2006.01.010

Source DB:  PubMed          Journal:  Parkinsonism Relat Disord        ISSN: 1353-8020            Impact factor:   4.891


  9 in total

1.  Pramipexole and compulsive masturbation.

Authors:  Randy A Sansone; Mark Ferlan
Journal:  Psychiatry (Edgmont)       Date:  2007-09

Review 2.  Antiparkinsonian medication and pathological gambling.

Authors:  Malcolm Lader
Journal:  CNS Drugs       Date:  2008       Impact factor: 5.749

3.  Dopaminergic-induced paraphilias associated with impulse control and related disorders in patients with Parkinson disease.

Authors:  Paolo Solla; Antonino Cannas; Maria Giovanna Marrosu; Francesco Marrosu
Journal:  J Neurol       Date:  2012-10-25       Impact factor: 4.849

Review 4.  Paraphilias and paraphilic disorders in Parkinson's disease: A systematic review of the literature.

Authors:  Paolo Solla; Marco Bortolato; Antonino Cannas; Cesare Salvatore Mulas; Francesco Marrosu
Journal:  Mov Disord       Date:  2015-03-11       Impact factor: 10.338

Review 5.  Behavioural adverse effects of dopaminergic treatments in Parkinson's disease: incidence, neurobiological basis, management and prevention.

Authors:  Angelo Antonini; Roberto Cilia
Journal:  Drug Saf       Date:  2009       Impact factor: 5.606

6.  Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study.

Authors:  T D L Steeves; J Miyasaki; M Zurowski; A E Lang; G Pellecchia; T Van Eimeren; P Rusjan; S Houle; A P Strafella
Journal:  Brain       Date:  2009-04-03       Impact factor: 13.501

Review 7.  Impulsive and compulsive behaviors in Parkinson's disease.

Authors:  Guoxin Zhang; Zhentao Zhang; Ling Liu; Jiaolong Yang; Jinsha Huang; Nian Xiong; Tao Wang
Journal:  Front Aging Neurosci       Date:  2014-11-14       Impact factor: 5.750

Review 8.  Hypersexuality in Parkinson's Disease: Systematic Review and Report of 7 New Cases.

Authors:  David Codling; Philip Shaw; Anthony S David
Journal:  Mov Disord Clin Pract       Date:  2015-04-30

9.  Diagnosis and treatment of impulse control disorders in patients with movement disorders.

Authors:  Tiago A Mestre; Antonio P Strafella; Teri Thomsen; Valerie Voon; Janis Miyasaki
Journal:  Ther Adv Neurol Disord       Date:  2013-05       Impact factor: 6.570

  9 in total

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