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Literature DB >> 16730007

Hormonal regulation of catechol-O-methyl transferase activity in women with uterine leiomyomas.

Salama A Salama¹, Shu-Leong Ho, Hui-Qun Wang, Jukka Tenhunen, Carola Tilgmann, Ayman Al-Hendy.

Abstract

Catechol-O-methyl transferase (COMT) expression is higher in leiomyomas compared with paired normal myometrium. The expression of COMT in leiomyoma cells is hormonally regulated-estrogen down-regulates, whereas P and dexamethasone up-regulate, COMT expression.

Entities: Chemical Disease Gene Species

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Year: 2006 PMID： 16730007 DOI： 10.1016/j.fertnstert.2005.12.049

Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329

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Cited

10 in total

1. 1,25-Dihydroxyvitamin D3 reduces TGF-beta3-induced fibrosis-related gene expression in human uterine leiomyoma cells.

Authors: Sunil K Halder; J Shawn Goodwin; Ayman Al-Hendy
Journal: J Clin Endocrinol Metab Date: 2011-02-02 Impact factor: 5.958

2. Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase.

Authors: Chakradhari Sharan; Sunil K Halder; Chandrasekhar Thota; Tarannum Jaleel; Sangeeta Nair; Ayman Al-Hendy
Journal: Fertil Steril Date: 2010-08-23 Impact factor: 7.329

3. Towards non-surgical therapy for uterine fibroids: catechol-O-methyl transferase inhibitor shrinks uterine fibroid lesions in the Eker rat model.

Authors: M H Hassan; H Fouad; S Bahashwan; A Al-Hendy
Journal: Hum Reprod Date: 2011-09-06 Impact factor: 6.918

Review 4. Evidence-Based Management of Uterine Fibroids With Botanical Drugs-A Review.

Authors: Masita Arip; Vi Lien Yap; Mogana Rajagopal; Malarvili Selvaraja; K Dharmendra; Sasikala Chinnapan
Journal: Front Pharmacol Date: 2022-06-22 Impact factor: 5.988

5. Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice.

Authors: Dong Zhang; Mohamed Al-Hendy; Gloria Richard-Davis; Valerie Montgomery-Rice; Chakradhari Sharan; Veera Rajaratnam; Anjali Khurana; Ayman Al-Hendy
Journal: Am J Obstet Gynecol Date: 2010-01-13 Impact factor: 8.661

6. Progesterone regulates catechol-O-methyl transferase gene expression in breast cancer cells: distinct effect of progesterone receptor isoforms.

Authors: Salama A Salama; Mohammad Jamaluddin; Raj Kumar; Memy H Hassan; Ayman Al-Hendy
Journal: J Steroid Biochem Mol Biol Date: 2007-06-30 Impact factor: 4.292

Hormonal regulation of catechol-O-methyl transferase activity in women with uterine leiomyomas.

1. 1,25-Dihydroxyvitamin D3 reduces TGF-beta3-induced fibrosis-related gene expression in human uterine leiomyoma cells.

2. Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase.

3. Towards non-surgical therapy for uterine fibroids: catechol-O-methyl transferase inhibitor shrinks uterine fibroid lesions in the Eker rat model.

Review 4. Evidence-Based Management of Uterine Fibroids With Botanical Drugs-A Review.

5. Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice.

6. Progesterone regulates catechol-O-methyl transferase gene expression in breast cancer cells: distinct effect of progesterone receptor isoforms.

7. Racial and ethnic differences in the pathogenesis and clinical manifestations of uterine leiomyoma.

8. Expression and cyclic variations of catechol-O-methyl transferase in human endometrial stroma.

9. Treatment of symptomatic uterine fibroids with green tea extract: a pilot randomized controlled clinical study.

Review 10. The Evolving Role of Natural Compounds in the Medical Treatment of Uterine Fibroids.