Literature DB >> 16729721

Autophagy: A protective mechanism in response to stress and inflammation.

Dominique Heymann1.   

Abstract

Autophagy is one of the intracellular systems that is responsible for protein trafficking (degradation/recycling) in eukaryotic cells. This ubiquitous process contributes to cytosolic homeostasis, but its deregulation is often associated with various pathologies, including neurodegenerative diseases and cancer and pathologies with an altered inflammatory response. This review provides an overview of autophagy and discusses its regulation, function and future therapeutic possibilities, with a focus on the role of autophagy in inflammation.

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Year:  2006        PMID： 16729721      PMCID： PMC3425450     

Source DB:  PubMed          Journal:  Curr Opin Investig Drugs        ISSN： 1472-4472


  67 in total

Review 1.  Bacterial interactions with the autophagic pathway.

Authors:  Brian R Dorn; William A Dunn; Ann Progulske-Fox
Journal:  Cell Microbiol       Date:  2002-01       Impact factor: 3.715

Review 2.  Peroxisome turnover by micropexophagy: an autophagy-related process.

Authors:  Jean-Claude Farré; Suresh Subramani
Journal:  Trends Cell Biol       Date:  2004-09       Impact factor: 20.808

Review 3.  Methods for monitoring autophagy.

Authors:  Noboru Mizushima
Journal:  Int J Biochem Cell Biol       Date:  2004-12       Impact factor: 5.085

4.  Growth factor regulation of autophagy and cell survival in the absence of apoptosis.

Authors:  Julian J Lum; Daniel E Bauer; Mei Kong; Marian H Harris; Chi Li; Tullia Lindsten; Craig B Thompson
Journal:  Cell       Date:  2005-01-28       Impact factor: 41.582

Review 5.  Pharmacological manipulation of cell death: clinical applications in sight?

Authors:  Douglas R Green; Guido Kroemer
Journal:  J Clin Invest       Date:  2005-10       Impact factor: 14.808

Review 6.  The ubiquitin system.

Authors:  A Hershko; A Ciechanover
Journal:  Annu Rev Biochem       Date:  1998       Impact factor: 23.643

7.  Inhibition of macroautophagy triggers apoptosis.

Authors:  Patricia Boya; Rosa-Ana González-Polo; Noelia Casares; Jean-Luc Perfettini; Philippe Dessen; Nathanael Larochette; Didier Métivier; Daniel Meley; Sylvie Souquere; Tamotsu Yoshimori; Gérard Pierron; Patrice Codogno; Guido Kroemer
Journal:  Mol Cell Biol       Date:  2005-02       Impact factor: 4.272

8.  Inhibition of macroautophagy and proteolysis in the isolated rat hepatocyte by a nontransportable derivative of the multiple antigen peptide Leu8-Lys4-Lys2-Lys-beta Ala.

Authors:  G Miotto; R Venerando; O Marin; N Siliprandi; G E Mortimore
Journal:  J Biol Chem       Date:  1994-10-14       Impact factor: 5.157

9.  Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells.

Authors:  L Jia; R R Dourmashkin; P D Allen; A B Gray; A C Newland; S M Kelsey
Journal:  Br J Haematol       Date:  1997-09       Impact factor: 6.998

10.  Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer.

Authors:  Eric Raymond; Jérôme Alexandre; Sandrine Faivre; Karina Vera; Eric Materman; Joseph Boni; Cathie Leister; Joan Korth-Bradley; Axel Hanauske; Jean-Pierre Armand
Journal:  J Clin Oncol       Date:  2004-05-10       Impact factor: 44.544
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  17 in total

1.  Identification of autophagy signaling network that contributes to stroke in the ischemic rodent brain via gene expression.

Authors:  Kun Liang; Lei Zhu; Jinyun Tan; Weihao Shi; Qing He; Bo Yu
Journal:  Neurosci Bull       Date:  2015-08-08       Impact factor: 5.203

2.  Paeoniflorin protects HUVECs from AGE-BSA-induced injury via an autophagic pathway by acting on the RAGE.

Authors:  Yufang Chen; Xing Du; Yande Zhou; Yanlin Zhang; Yaping Yang; Zhihua Liu; Chunfeng Liu; Ying Xie
Journal:  Int J Clin Exp Pathol       Date:  2015-01-01

Review 3.  Negative regulation of autophagy.

Authors:  C Liang
Journal:  Cell Death Differ       Date:  2010-09-24       Impact factor: 15.828

Review 4.  The emerging role of autophagy in the pathophysiology of diabetes mellitus.

Authors:  Claudio D Gonzalez; Myung-Shik Lee; Piero Marchetti; Massimo Pietropaolo; Roberto Towns; Maria I Vaccaro; Hirotaka Watada; John W Wiley
Journal:  Autophagy       Date:  2011-01-01       Impact factor: 16.016

5.  An increased autophagic flux contributes to the anti-inflammatory potential of urolithin A in macrophages.

Authors:  Yaw Duah Boakye; Laura Groyer; Elke H Heiss
Journal:  Biochim Biophys Acta Gen Subj       Date:  2017-10-12       Impact factor: 3.770

6.  ERK and Akt signaling pathways are involved in advanced glycation end product-induced autophagy in rat vascular smooth muscle cells.

Authors:  Pengfei Hu; Dongwu Lai; Peilin Lu; Jing Gao; Hong He
Journal:  Int J Mol Med       Date:  2012-01-23       Impact factor: 4.101

7.  Inhibition of CLIC4 enhances autophagy and triggers mitochondrial and ER stress-induced apoptosis in human glioma U251 cells under starvation.

Authors:  Jiateng Zhong; Xiaoxia Kong; Hongyu Zhang; Chunyan Yu; Ye Xu; Jinsong Kang; Huimei Yu; Haowei Yi; Xiaochun Yang; Liankun Sun
Journal:  PLoS One       Date:  2012-06-25       Impact factor: 3.240

8.  Methotrexate and theaflavin-3, 3'-digallate synergistically restore the balance between apoptosis and autophagy in synovial fibroblast of RA: an ex vivo approach with cultured human RA FLS.

Authors:  Sanchaita Misra; Aniruddha Bagchi; Avik Sarkar; Sougata Niyogi; Dipanjan Bhattacharjee; Sulagna Chatterjee; Sumantro Mondal; Arghya Chattopadhyay; Ayindrila Saha; Sudipta Chatterjee; Pradyot Sinhamahapatra; Partha Chakrabarti; Mitali Chatterjee; Alakendu Ghosh
Journal:  Inflammopharmacology       Date:  2021-08-05       Impact factor: 4.473

9.  Role of TFEB Mediated Autophagy, Oxidative Stress, Inflammation, and Cell Death in Endotoxin Induced Myocardial Toxicity of Young and Aged Mice.

Authors:  Fang Li; Fangfang Lang; Huilin Zhang; Liangdong Xu; Yidan Wang; Enkui Hao
Journal:  Oxid Med Cell Longev       Date:  2016-04-21       Impact factor: 6.543

10.  Intragraft transcriptional profiling of renal transplant patients with tubular dysfunction reveals mechanisms underlying graft injury and recovery.

Authors:  Hátylas Azevedo; Paulo Guilherme Renesto; Rogério Chinen; Erika Naka; Ana Cristina Carvalho de Matos; Marcos Antônio Cenedeze; Carlos Alberto Moreira-Filho; Niels Olsen Saraiva Câmara; Alvaro Pacheco-Silva
Journal:  Hum Genomics       Date:  2016-01-07       Impact factor: 4.639
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