Literature DB >> 16729120

The synthesis of tethered ligand dimers for PPARgamma-RXR protein heterodimers.

Debra L Mohler1, Gang Shen.   

Abstract

Heterodimeric compounds based on tethering the PPARgamma agonist Rosiglitazone to the RXR ligand Targretin have been prepared.

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Year:  2006        PMID： 16729120     DOI： 10.1039/b600848h

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

1.  Stereoselective synthesis of light-activatable perfluorophenylazide-conjugated carbohydrates for glycoarray fabrication and evaluation of structural effects on protein binding by SPR imaging.

Authors:  Lingquan Deng; Oscar Norberg; Suji Uppalapati; Mingdi Yan; Olof Ramström
Journal:  Org Biomol Chem       Date:  2011-03-18       Impact factor: 3.876

2.  Convergent synthesis of a steroidal antiestrogen-mitomycin C hybrid using "click" chemistry.

Authors:  Robert N Hanson; Edward Hua; David Labaree; Richard B Hochberg; Kyle Proffitt; John M Essigmann; Robert G Croy
Journal:  Org Biomol Chem       Date:  2012-09-25       Impact factor: 3.876

3.  Development of a new thiol site-specific prosthetic group and its conjugation with [Cys(40)]-exendin-4 for in vivo targeting of insulinomas.

Authors:  Xuyi Yue; Dale O Kiesewetter; Jinxia Guo; Zhongchan Sun; Xiaoxiang Zhang; Lei Zhu; Gang Niu; Ying Ma; Lixin Lang; Xiaoyuan Chen
Journal:  Bioconjug Chem       Date:  2013-06-28       Impact factor: 4.774

4.  Synthesis and preclinical characterization of [18F]FPBZA: a novel PET probe for melanoma.

Authors:  Shih-Yen Wu; Shih-Pin Huang; Yen-Chen Lo; Ren-Shyan Liu; Shyh-Jen Wang; Wuu-Jyh Lin; Chih-Chieh Shen; Hsin-Ell Wang
Journal:  Biomed Res Int       Date:  2014-09-01       Impact factor: 3.411
  4 in total

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